Publications by authors named "Jiangqi Hou"
Article Synopsis
- Dihuang Yinzi (DHYZ) is a traditional Chinese medicine with established benefits for Alzheimer's disease (AD), but the specific molecular mechanisms are not fully understood and need more research.
- The study aims to explore how DHYZ promotes mitochondrial biogenesis through the AMPK/SIRT1/PGC-1α pathway, aiming to reduce neuronal loss and memory impairments in mice with AD.
- Results show that DHYZ significantly enhances cognitive function, reduces neuron loss, and improves mitochondrial health in AD model mice, indicating its potential therapeutic role in treating AD effects.
Objective: The aim of this study was to systematically evaluate the therapeutic effects of Dihuang Yinzi decoction on Alzheimer's disease (AD) and provide a medical evidence-based clinical application of traditional Chinese medicine (TCM).
Methods: A comprehensive search was conducted across multiple databases, including PubMed, Embase, Cochrane Library, China National Journals Full-text Database, VIP Database for Chinese Technical Periodicals, Wan Fang database, and SinoMed database, to collect clinical randomized controlled trials of Dihuang Yinzi decoction in the treatment of AD. Strict literature screening was performed based on predefined inclusion and exclusion criteria.