Tetramethylpyrazine promotes osteo-angiogenesis during bone fracture repair.

Background: Nonunion following a long bone fracture has gained a lot of attention due to the dreadful impact on the life quality of tremendous patients. Recent data have demonstrated the important involvement of angiogenesis in improving fracture healing. Tetramethylpyrazine (TMP) is an active component of Chinese herbal medicine with various biological activities including pro-angiogenesis property.

Activation of Dusp14 protects against osteoclast generation and bone loss by regulating AMPKα-dependent manner.

Osteoporosis is a progressive systematic skeletal disorder featured by decreased bone and enhanced risk of fracture due to an uncoupling of bone resorption. Chronic inflammatory response plays an essential role in osteoporosis progression. Unfortunately, the pathogenesis that contributes to osteoporosis still remains unclear.

Video Captioning by Adversarial LSTM.

In this paper, we propose a novel approach to video captioning based on adversarial learning and Long-Short Term Memory (LSTM). With this solution concept we aim at compensating for the deficiencies of LSTM-based video captioning methods that generally show potential to effectively handle temporal nature of video data when generating captions, but that also typically suffer from exponential error accumulation. Specifically, we adopt a standard Generative Adversarial Network (GAN) architecture, characterized by an interplay of two competing processes: a "generator", which generates textual sentences given the visual content of a video, and a "discriminator" which controls the accuracy of the generated sentences.

[Expression of receptor activator of nuclear factor kappaB ligand and osteoprotegerin of mice osteoblast induced by metal ions].

Objective: Lots of metal ions accumulation and over-expression of receptor activator of NF-kappaB ligand (RANKL) around the prosthesis could be found in revision of total hip arthroplasty. To investigate the relationship between metal ions and aseptic loosening by observing the effects of Co2+ and Cr3+ ions on the expression of RANKL and osteoprotegerin (OPG) from osteoblast.

Methods: Osteoblasts were cultured in vitro at the density of 1 x 10(5) cells/mL, and were divided into 2 groups according to different culture solutions.