Publications by authors named "Jiang-hua Zhu"

Background: Preoperative posterior tilt is a risk factor for fixation failure in femoral neck fractures. This study aimed to evaluate the configuration of anterior positioning screw in proximal femoral plating in the treatment of retroverted femoral neck fractures in terms of resisting posterior tilt.

Methods: We retrospectively analyzed patients with retroverted femoral neck fractures who were fixed by proximal femoral plating from January 2014 to August 2019.

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Purpose: Pauwels type-3 femoral neck fractures are challenging injuries to manage with high rates of complications after internal fixation and no consensus has been reached regarding the optimal fixation construct. The current study aims to evaluate the effect of dynamic limited axial compression in parallel screws combined with medial buttress plate (SMBP) or lateral compression plate (LCP) fixation of Pauwels type-3 femoral neck fractures.

Methods: We performed a retrospective analysis of 51 cases of Pauwels type-3 femoral neck fractures who were fixed by SMBP or LCP.

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Activation of the Ca/calmodulin-dependent protein kinase II isoform δA (CaMKIIδA) disturbs intracellular Ca homeostasis in cardiomyocytes during chronic heart failure (CHF). We hypothesized that upregulation of CaMKIIδA in cardiomyocytes might enhance Ca leak from the sarcoplasmic reticulum (SR) via activation of phosphorylated ryanodine receptor type 2 (P-RyR2) and decrease Ca uptake by inhibition of SR calcium ATPase 2a (SERCA2a). In this study, CHF was induced in rats by ligation of the left anterior descending coronary artery.

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A novel amphiphilic imidazolium-based probe containing a dansyl fluorophore and a long cetyl chain has been developed for ATP recognition. The probe forms self-assembled micelle-like aggregates at low concentration in its aqueous solution and can selectively recognize ATP among other bioactive anions with a significant enhancement in fluorescence emission.

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A novel pyrene-functionalized polynorbornene (P1) bearing sulfonamide NH and triazolium donors has been synthesized for ratiometric fluorescence sensing of PPi in aqueous solution. In addition, P1 is also used to monitor intracellular PPi and to detect PPi released during polymerase chain reaction.

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Recently, more and more rhodamine derivatives have been used as fluorophores to construct sensors due to their excellent spectroscopic properties. A rhodamine-based fluorescent and colorimetric Fe(3+) chemosensor 3',6'-bis(ethylamino)-2-acetoxyl-2',7'-dimethyl-spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one (RAE) was designed and synthesized. Upon the addition of Fe(3+), the dramatic enhancement of both fluorescence and absorbance intensity, as well as the color change of the solution, could be observed.

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Objective: To investigate the effect of four different anesthetic methods (combined epidural with general anesthesia with endotracheal intubation or with laryngeal mask airway, total intravenous anesthesia or remifentanil intravenous infusion combined with inhalational anesthesia) on stress reaction in patients undergoing upper abdominal surgery.

Methods: Sixty ASAI-II patients, aged 18 - 65 y, scheduled for elective upper abdominal surgery were enrolled in the study. They were divided into four groups: epidural combine general anesthesia with intubation group (EG group) and with laryngeal mask group (EGL group), total intravenous remifentanil combined with propofol (RP group) and inhalational group (RI group).

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OBJECTIVE: To investigate the expression of soluble intercellular adhesion molecule-1(sICAM-1) and CD11a/CD18 in coronary heart disease(CHD). METHODS: The sICAM-1 and CD11a/CD18 levels were measured by ELISA and flow cytlemetry in 76 CHD patients and 65 healthy subjects. RESULTS: The level of sICAM-1 and CD11a/CD18 were significantly higher in CHD patients than healthy subjects [SICAM-1(g/L):263.

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