Biologic response to autogenous particulate bone graft and shaped titanium mesh in segmental mandibular defect reconstruction.

Purpose: This study evaluated the biologic response to titanium mesh and autogenous particulate bone grafts for the reconstruction of segmental mandibular defects in a dog model.

Materials And Methods: Unilateral 40-mm critical-sized continuity defects of the mandible were made in five beagle dogs. Titanium mesh was shaped and fixed with titanium screws in the defects.

[Experimental study of the shaped titanium mesh combined with autogenous particulate bone graft and simultaneous implant for reconstructing segmental mandibular defect].

Objective: To observe the healing and bone formation of the autogenous particulate bone graft and osseointegration of the implants in shaped titanium mesh with autogenous particulate bone graft and simultaneous implant for reconstructing segmental mandibular defect in dogs.

Methods: Five Beagle dogs were prepared with unilateral 40 mm segmental mandibular defect. Titanium mesh was shaped according to the mandibular defect and was fixed with titanium screws.