Publications by authors named "Jiang-Shui Liang"
Tumor microenvironment (TME) regulated the development of the Lung squamous cell carcinoma (LUSC). To know more about the LUSC, this study tried to figure the role of fscin actin-bundling protein 1 (FSCN1) in the TME. We identified the FSCN1 as the hub immune gene in LUSC, with the use of weighted gene co-expression network analysis (WGCNA) and the Human Protein Atlas.
View Article and Find Full Text PDFAlthough invasive thymoma commonly infiltrates neighbouring mediastinal structures, its extension into the superior vena cava (SVC) and consequent SVC occlusion are rare. In such cases, the urgent removal of the thymoma and radical resection of the infiltrated SVC representreasonable options, since induction therapy is time-consuming and useless for symptom resolution. A case of invasive thymoma extending into the SVC and right atrium (RA) with SVC syndrome is reported.
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- The study investigated the effects of the demethylating agent 5-aza-2'-deoxycytidine (5-Aza-CdR) on non-small cell lung cancer (NSCLC) A549 cells, focusing on cell proliferation and TFPI-2 gene expression.
- MTT assays revealed that treatment with 5-Aza-CdR significantly inhibited A549 cell growth, while flow cytometry indicated that higher concentrations led to increased cell cycle arrest in the G0/G1 phase.
- Results showed that 5-Aza-CdR treatment caused demethylation of the TFPI-2 gene promoter and a corresponding increase in both mRNA and protein expression levels of the TFPI-