Salvage interstitial brachytherapy based on computed tomography for recurrent cervical cancer after radical hysterectomy and adjuvant radiation therapy: case presentations and introduction of the technique.

Purpose: Locally recurring cervical cancer after surgery and adjuvant radiotherapy remains a major therapeutic challenge. This paper presents a new therapeutic technique for such patients: interstitial brachytherapy (BT) guided by real-time three-dimensional (3D) computed tomography (CT).

Material And Methods: Sixteen patients with recurrent cervical cancer after radical surgery and adjuvant external-beam radiotherapy (EBRT) were included in this study.

Imaging and histologic features of traumatic temporomandibular joint ankylosis.

Objective: We aimed to study the pathology underlying traumatic temporomandibular joint ankylosis (TMJA).

Study Design: Specimens from 10 patients with traumatic TMJA were categorized using the Sawhney classification and were decalcified and stained with hematoxylin-eosin, alcian blue/periodic acid-Schiff, alizarin red, and Masson stains. Immunostaining with anti-CD34 antibody was performed.

A pilot trial on the molecular pathophysiology of traumatic temporomandibular joint bony ankylosis in a sheep model. Part II: The differential gene expression among fibrous ankylosis, bony ankylosis and condylar fracture.

Objective: The purpose of the study was to preliminarily explore the differential expressions of a series of genes regulating bone formation in temporomandibular joint (TMJ) fibrous ankylosis, bony ankylosis and condylar fracture healing.

Methods: The cDNA from either the bony ankylosed callus or fracture callus of the 6 sheep, as described in the part I, were both used in the study. The differences of gene expressions between bony ankylosis and condylar fracture at 1, 3, and 6 months postoperatively were measured by real-time PCR, with 2 samples at each time point.

A pilot trial on the molecular pathophysiology of traumatic temporomandibular joint bony ankylosis in a sheep model. Part I: Expression of Wnt signaling.

Objective: To preliminarily investigate the temporal patterns of the endogenous mRNA expression for members of the Wnt signaling and a series of genes regulating bone formation during the development of traumatic temporomandibular joint (TMJ) bony ankylosis in a sheep model.

Methods: Six sheep were used for the induction of bony ankylosis of TMJ. We performed a condylar fracture, excision of the lateral 2/3 disc and serious injury to the glenoid fossa to induce bony ankylosis on the right TMJ.

Ankylosing spondylitis associated with bilateral ankylosis of the temporomandibular joint.

Objective: The objective of this study was to analyze the clinical and laboratory features, treatments, and prognosis of ankylosing spondylitis (AS) associated with bilateral temporomandibular joint ankylosis (TMJA).

Methods: A PubMed search was conducted from 1966 to date, and the references of published studies were also checked to identify additional cases. Information from these reports and our report were compared and analyzed.

Surgical induction of TMJ bony ankylosis in growing sheep and the role of injury severity of the glenoid fossa on the development of bony ankylosis.

Objective: The purpose of this paper is to summarize our experiences in creating an animal model of TMJ bony ankylosis based on 2 sequential experiments.

Methods: Two sequential experiments were performed with the aim of creating a model of TMJ bony ankylosis. Seven growing sheep were used in the first experiment, in which 1 was served as a control animal.

[Experimental establishment of animal model of temporomandibular joint ankylosis secondary to condylar sagittal fracture].

Objective: To experimentally develop an animal model of traumatic temporomandibular joint ankylosis secondary to condylar fracture in small Tail Han sheep.

Methods: Four sheep were used to make sagittal fracture of condyles. The cartilage layer of articular surface was damaged and lateral half of articular disc was removed in the right side and conserved in the left side as a control.

[Application of 3-D skull models and guide plates in the treatment of unilateral orbitozygomatic deformity after fracture].

Objective: To discuss the application of 3-D skull models and guide plates in treatment of unilateral orbitozygomatic deformity after fracture.

Methods: Each patient underwent CT scan and DICOM data was obtained preoperatively. Two 3-D resin skull models were produced by rapid prototyping technique.

[Prosthetic replacement of condylar head for management of traumatic temporomandibular joint ankylosis].

Objective: To preliminarily evaluate the method of using titanium condylar protheses in management of traumatic temporomandibular joint ankylosis.

Methods: Between August 2006 and April 2008, titanium condylar replacement was performed in 5 male patients. Preoperative CT datum of patient was obtained and a resin model was then produced and used as a reference to select a suitable titanium condyle for reconstruction of the joint.