Publications by authors named "Jiang-Li Lu"
Background: Bacillus Calmette-Guérin (BCG) is capable of enhancing the infiltration of immune cells into the tumour. However the temporal dynamics of immune cell patterns in patients receiving BCG instillation remains unclear.
Methods: Ninety-six patients who underwent intravesical BCG therapy, comprising 46 responders and 50 non-responders, were retrospectively enroled to explore the evolving immune landscape.
Article Synopsis
- Neoadjuvant immune checkpoint blockade combined with chemoradiotherapy shows promising results for patients with locally advanced esophageal squamous cell carcinoma, but the impact on the tumor immune microenvironment requires further study.
- In a study of 41 patients, tissue samples were analyzed before and after treatment to observe changes in immune cell patterns, revealing that different immune responses are linked to pathologic complete response (pCR) status.
- Results indicated that pCR patients had fewer CD86+ cells post-treatment, while non-pCR patients showed increased CD86+ cell density, highlighting the complex interactions of immune cells during therapy.
Purpose: Urachal cancer is similar to gastrointestinal adenocarcinoma in histology, and gastroscopy/colonoscopy is often administered during perioperative evaluation. However, gastroscopy and colonoscopy have corresponding disadvantages. This study discusses whether gastroscopy/colonoscopy is truly necessary for patients with urachal cancer.
View Article and Find Full Text PDFObjective: There is no consensus regarding the best interval time between transurethral resection of a bladder tumor and Bacillus Calmette-Guerin (BCG) perfusion. This study was to explore whether the interval time has an impact on the prognosis and adverse effects.
Methods: We retrospectively reviewed the clinical data of patients who received BCG intravesical perfusion at Sun Yat-sen University Cancer Center (SYSUCC) from September 2015 to October 2021.