Association Analysis of Hyperlipidemia with the 28-Day All-Cause Mortality of COVID-19 in Hospitalized Patients.

Objective This study aimed to determine the association of hyperlipidemia with clinical endpoints among hospitalized patients with COVID-19, especially those with pre-existing cardiovascular diseases (CVDs) and diabetes. Methods This multicenter retrospective cohort study included all patients who were hospitalized due to COVID-19 from 21 hospitals in Hubei province, China between December 31, 2019 and April 21, 2020. Patients who were aged < 18 or ≥ 85 years old, in pregnancy, with acute lethal organ injury (e.

No significant association between dipeptidyl peptidase-4 inhibitors and adverse outcomes of COVID-19.

Background: Dipeptidyl peptidase-4 (DPP4) is commonly targeted to achieve glycemic control and has potent anti-inflammatory and immunoregulatory effects. Recent structural analyses indicated a potential tight interaction between DPP4 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), raising a promising hypothesis that DPP4 inhibitor (DPP4i) drugs might be an optimal strategy for treating coronavirus disease 2019 (COVID-19) among patients with diabetes. However, there has been no direct clinical evidence illuminating the associations between DPP4i use and COVID-19 outcomes.

[Prevalence of Sarcopenia and Associated Factors in Community-dwelling Elderly Populations in Chengdu China].

Objective: To determine the prevalence of sarcopenia in community-dwelling elderly populations in Chengdu and its associated risk factors.

Methods: A total of 947 community dwelling residents aged ≥60 yr. in Chengdu participated in this study.

Noninvasive evaluation of nonalcoholic fatty liver disease: Current evidence and practice.

With the increasing number of individuals with diabetes and obesity, nonalcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent, affecting one-quarter of adults worldwide. The spectrum of NAFLD ranges from simple steatosis or nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH). NAFLD, especially NASH, may progress to fibrosis, leading to cirrhosis and hepatocellular carcinoma.

[Comparison of three HIV antibody confirmatory assay kits in confirming early HIV infection].

Objective: This study was to compare the performance of three HIV antibody confirmatory assay kits in confirming early HIV infection.

Methods: Five HIV antibody-positive plasma specimens were ten-fold serially diluted and then detected by ELISA. The above diluted specimens were detected with the following three HIV antibody confirmatory assay kits to analyze their sensitivity, including Wantai-RIBA (Recombinant immunoblot assay, Beijing Wantai Biological Pharmacy, China), MP-WB (HIV Blot 2.

[Evaluation of BED-CEIA assay with dried blood spot specimens in China].

Unlabelled: OBJECTIVE; To study the feasibility of using dried blood spot (DBS) specimens in BED-CEIA assay and to estimate the HIV-1 incidence with DBS in China.

Methods: 10 313 participants from 27 voluntary counseling and testing (VCT) sites were enrolled in this study. Both plasma and DBS specimens were collected.

[The preparation and characterization of sol-gel derived zinc modified carbonated hydroxyapatite].

Objective: To prepare zinc-modified carbonated hydroxyapatite (Zn-CHA) coating material via sol-gel method and explore the influence of zinc substitution on physical and chemical properties of biomaterial samples.

Methods: Two kinds of samples with different zinc content and Ca/P molar ratio were prepared. One was fabricated with 4% zinc and the Ca/P molar ratio was 1.

[The experimental study on biodegradable gel membrane applied to prevention of postoperative adhesion of abdominal cavity surgery].

Objective: To develop a new type of anti-adhesion gel membrane and explore its applying technique.

Methods: 24 adult New Zealand white rabbits were used for the experiment research project, the animals were divided into two groups: the experiment group (18 adult New Zealand white rabbits) and the control group (6 adult New Zealand white rabbits). The animal models were established via the abdominal cavity.