Publications by authors named "Jiang Gg"
Systemic lupus erythematosus (SLE) is a classic autoimmune disease characterized by abnormal autoantibodies, immune complex deposition, and tissue inflammation. Despite extensive research, the exact etiology and progression of SLE remain elusive. Cytidine/uridine monophosphate kinase 2 (CMPK2), a mitochondrial nucleoside monophosphate kinase, has garnered attention for its potential involvement in the development of various diseases, including SLE, where it has been observed to be dysregulated in affected individuals.
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- - Two closely related plant species, Chimonanthus praecox and Chimonanthus salicifolius, diverged about six million years ago and have different flowering times, with C. praecox blooming in early spring and C. salicifolius in autumn, but both can endure short periods of cold at -15 °C.
- - The study identified a total of 33 SBP (SQUAMOSA promoter-binding protein) genes in these species, examining their chromosomal locations, structures, and conserved motifs, finding 15 in C. praecox and 18 in C. salicifolius.
- - Analysis of gene expression showed that more SBP genes were less active in
Article Synopsis
- MIKC type MADS-box transcription factors are crucial for regulating flowering time and flower development, and this study focuses on their role in Chimonanthus salicifolius, a plant with unique flowering characteristics.
- * The research reveals a total of 29 MIKC-type MADS-box genes in C. salicifolius, highlighting their evolutionary relationships and how certain gene structures and expression patterns differ from other species like Arabidopsis and Chimonanthus praecox.
- * The findings suggest that the absence of certain repressor genes and the expansion of specific promoter genes may explain the early flowering and distinct morphology of C. salicifolius compared to related species.
Background: The incidence of cognitive dysfunction in diabetes is increasing yearly, which severely affects the quality of life of patients and places a heavy burden on families and society. It has been demonstrated that impaired clearance of cerebral amyloid β-protein (Aβ) is a central event in the initiation and progression of Aβ deposition and cognitive impairment in diabetic patients. However, until now, the molecular mechanism by which diabetes mellitus induces impaired clearance of Aβ has remained unclear.
View Article and Find Full Text PDFBackground: In December 2019, the cases of pneumonia of unknown etiology emerged in Wuhan, China, and rapidly spread throughout the country. The disease was later designated by the World Health Organization (WHO) as Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2). Few studies have assessed the clinical characteristics of COVID-19 and control strategies used to mitigate disease spread in high-altitude plateau regions of China.
View Article and Find Full Text PDFObjective: To explore the reliability and validity of the Children's Impact of Event Scale (Chinese version, CRIES-13) and to determine the value and the optimal cutoff point of the score of CRIES-13 in screening posttraumatic stress disorder (PTSD), so as to provide evidence for PTSD prevention and identify children at risk in Wenchuan earthquake areas.
Methods: A total of 253 children experienced the Wenchuan earthquake were tested through Stratified random cluster sampling. The authors examined CRIES-13's internal consistency, discriminative validity and predictive value of the cut-off.