Publications by authors named "Jiang Chuan Dong"
Article Synopsis
- - The study explores the connection between 25-hydroxyvitamin D (25-(OH)D), vitamin B12, and cognitive frailty, using data from the National Health and Nutrition Examination Survey (NHANES).
- - Researchers found a negative correlation, showing that higher levels of 25-(OH)D are linked to a reduced risk of cognitive frailty in older adults, with a 12% risk reduction for each unit increase in vitamin D levels.
- - While the findings suggest a significant relationship between vitamin D and cognitive frailty, the authors call for more detailed longitudinal studies to confirm these results.
Coupled with the ageing population, frailty, characterized by high prevalence and difficult treatment, has progressively evolved into a significant public health concern. Frail individuals can often observe serious metabolic disorders and sleep-wake cycle disruption, which may be caused by the decline in physiological reserve and increased vulnerability. Moreover, sleep-wake cycle disruptions and metabolic dysfunctions associated with circadian rhythm disorders are considered to be a central part of the disorder.
View Article and Find Full Text PDFThymic stromal lmphopoietin pomotes macrophage-derived foam cell formation.
J Huazhong Univ Sci Technolog Med Sci
February 2014
The effect of thymic stromal lymphopoietin (TSLP) on macrophage-derived foam cell formation and the underlying mechanism were studied. Macrophages isolated from C57BL/6 mice were co-cultured in vitro with different concentrations of TSLP or TSLPR-antibody in the presence of oxidized low density lipoprotein (ox-LDL). The effects of TSLP on macrophage-derived foam cell formation were observed by using oil red O staining and intracellular lipid determination.
View Article and Find Full Text PDF