A novel carboxyl polymer-modified upconversion luminescent nanoprobe for detection of prostate-specific antigen in the clinical gray zonebase by flow immunoassay strip.

Prostate specific antigen (PSA) is a widely-used biomarker for the diagnosis, screening, and prognosis of prostate cancer (PCa). It is critical to develop a rapid and convenient method to accurately detect PSA levels, especially when the PSA levels are in the clinical gray area of 4-10 ng/mL. We developed a novel upconversion nanoparticle (UCNP)-based fluorescence lateral flow test strip for qualitatively and quantitatively detecting PSA.

Molecular cytogenetic characterization and phylogenetic analysis of four species (Poaceae).

Chromosomes of four (Andersson, 1855) species including (Andersson, 1855), (Schumann & Lauterb, 1901), (Hackel, 1882) and (Chen & Renvoize, 2005) were analyzed using sequentially combined PI and DAPI (CPD) staining and fluorescence hybridization (FISH) with 45S rDNA probe. To elucidate the phylogenetic relationship among the four species, the homology of repetitive sequences among the four species was analyzed by comparative genomic hybridization (cGISH). Subsequently four species were clustered based on the internal transcribed spacer (ITS) of 45S rDNA.

An evaluation study of research efficiency of the Guangzhou institute of respiratory diseases based on malmquist index.

Background: This study aimed to analyze the dynamic changes of the scientific research innovation efficiency of Guangzhou Institute of Respiratory Diseases (GIRD) during the year 2009-2013 to explore the reason for these changes and give some suggestions on how to improve the overall efficiency of the Institute.

Methods: The panel data used in this study were taken from 19 research teams of GIRD during 2009 to 2013. Data envelopment analysis (DEA) based on Malmquist index (MI) was used to analyze the performance of each research team in terms of productivity changes over time.

High-resolution plasmonic structural colors from nanohole arrays with bottom metal disks.

We present transmissive plasmonic structural colors from subwavelength nanohole arrays with bottom metal disks for scaled-up manufacturing by nanoimprint lithography (NIL). Comprehensive theoretical and experimental studies are carried out to understand the specific extraordinary optical transmission behavior of the structures with such bottom metal disks. Distinctive colors covering the entire visible spectrum can be generated by changing the structural dimensions of hole arrays in Ag covered by the metal disks.