Discrepant soil microbial community and C cycling function responses to conventional and biodegradable microplastics.

Biodegradable microplastics (MPs) are promising alternatives to conventional MPs and are of high global concern. However, their discrepant effects on soil microorganisms and functions are poorly understood. In this study, polyethylene (PE) and polylactic acid (PLA) MPs were selected to investigate the different effects on soil microbiome and C-cycling genes using high-throughput sequencing and real-time quantitative PCR, as well as the morphology and functional group changes of MPs, using scanning electron microscopy and Fourier transform infrared spectroscopy, and the driving factors were identified.

[Alzheimer's disease classification based on nonlinear high-order features and hypergraph convolutional neural network].

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that damages patients' memory and cognitive abilities. Therefore, the diagnosis of AD holds significant importance. The interactions between regions of interest (ROIs) in the brain often involve multiple areas collaborating in a nonlinear manner.

Intelligent surgical workflow recognition for endoscopic submucosal dissection with real-time animal study.

Recent advancements in artificial intelligence have witnessed human-level performance; however, AI-enabled cognitive assistance for therapeutic procedures has not been fully explored nor pre-clinically validated. Here we propose AI-Endo, an intelligent surgical workflow recognition suit, for endoscopic submucosal dissection (ESD). Our AI-Endo is trained on high-quality ESD cases from an expert endoscopist, covering a decade time expansion and consisting of 201,026 labeled frames.

FAFuse: A Four-Axis Fusion framework of CNN and Transformer for medical image segmentation.

Medical image segmentation is crucial for accurate diagnosis and treatment in the medical field. In recent years, convolutional neural networks (CNNs) and Transformers have been frequently adopted as network architectures in medical image segmentation. The convolution operation is limited in modeling long-range dependencies because it can only extract local information through the limited receptive field.

Single-Factor Comprehensive Reservoir Quality Classification Evaluation-Taking the Hala'alat Mountains at the Northwestern Margin of the Junggar Basin as an Example.

In the process of petroleum geology exploration and development, reservoir quality evaluation is an essential component. However, conventional reservoir quality evaluation methods are no longer able to provide accurate and comprehensive assessments for all types of reservoirs. Therefore, the comprehensive evaluation of reservoir quality using multiple single factors is of significant importance in improving the level of reservoir quality assessment and enhancing the effectiveness of oil and gas exploration techniques.

Sedimentary Characteristics and Hydrocarbon-Generation Potential of the Permian Pingdiquan Formation in Dongdaohaizi Sag, Junggar Basin, Northwest China.

After several years of extensive exploration, a series of oil and gas reservoirs or structures have been discovered in the Dongdaohaizi sag, situated in the hinterland of the Junggar Basin. However, in recent years, some wells around the sag have failed. Herein, sedimentary facies, the plane distribution of dark mudstone, geochemical characteristics of source rocks, and the control of sedimentary facies on the distribution and development of source rocks in the Permian Pingdiquan Formation in the Dongdaohaizi sag were systematically investigated.

Analysis of risk factors for severe acute kidney injury in patients with acute myocardial infarction: A retrospective study.

Background: Patients with acute myocardial infarction (AMI) complicated by acute kidney injury (AKI) tend to have a poor prognosis. However, the exact mechanism of the co-occurrence of the two diseases is unknown. Therefore, this study aims to determine the risk factors for severe AKI in patients with AMI.

Klotho alleviates contrast-induced acute kidney injury by suppressing oxidative stress, inflammation, and NF-KappaB/NLRP3-mediated pyroptosis.

Background: Contrast-induced acute kidney injury (CI-AKI) is a common complication following percutaneous coronary intervention in coronary artery disease (CAD) patients with >30% incidence. Klotho is a multifunctional protein that inhibits oxidative stress and inflammation, but its role in CI-AKI is poorly understood. The present study aimed to explore the effects of klotho in CI-AKI.

CELL INSTANCE SEGMENTATION VIA MULTI-SCALE NON-LOCAL CORRELATION.

For cell instance segmentation on Electron Microscopy (EM) images, state-of-the-art methods either conduct pixel-wise classification or follow a detection and segmentation manner. However, both approaches suffer from the enormous cell instances of EM images where cells are tightly close to each other and show inconsistent morphological properties and/or homogeneous appearances. This fact can easily lead to over-segmentation and under-segmentation problems for model prediction, , falsely splitting and merging adjacent instances.

A High-Accuracy, High Anti-Noise, Unbiased Frequency Estimator Based on Three CZT Coefficients for Deep Space Exploration Mission.

Deep space exploration navigation requires high accuracy of the Doppler measurement, which is equivalent to a frequency estimation problem. Because of the fence effect and spectrum leakage, the frequency estimation performances, which is based on the FFT spectrum methods, are significantly affected by the signal frequency. In this paper, we propose a novel method that utilizes the mathematical relation of the three Chirp-Z Transform (CZT) coefficients around the peak spectral line.

DLTTA: Dynamic Learning Rate for Test-Time Adaptation on Cross-Domain Medical Images.

Test-time adaptation (TTA) has increasingly been an important topic to efficiently tackle the cross-domain distribution shift at test time for medical images from different institutions. Previous TTA methods have a common limitation of using a fixed learning rate for all the test samples. Such a practice would be sub-optimal for TTA, because test data may arrive sequentially therefore the scale of distribution shift would change frequently.

Bioleaching of Chalcopyrite Waste Rock in the Presence of the Copper Solvent Extractant LIX984N.

Heap bioleaching, the solubilization of metal ions from metal sulfides by microbial oxidation, is often combined with solvent extraction (SX) and electrowinning to recover, e.g., copper from low-grade ores.

Identification of Key Exosome Gene Signature in Mediating Coronary Heart Disease by Weighted Gene Correlation Network Analysis.

Background: Coronary heart disease (CHD) is the most prevalent disease with an unelucidated pathogenetic mechanism and is mediated by complex molecular interactions of exosomes. Here, we aimed to identify differentially expressed exosome genes for the disease development and prognosis of CHD.

Method: Six CHD samples and 32 normal samples were downloaded from the exoRbase database to identify the candidate genes in the CHD.

Melatonin alleviates lipopolysaccharide-induced myocardial injury by inhibiting inflammation and pyroptosis in cardiomyocytes.

Background: Melatonin (MT) has been shown to protect against various cardiovascular diseases. However, the effect of MT on lipopolysaccharide (LPS)-induced myocardial injury is poorly understood. This study aims to evaluate the effects of MT on LPS-induced myocardial injury .

Establishment of a morphological atlas of the Caenorhabditis elegans embryo using deep-learning-based 4D segmentation.

The invariant development and transparent body of the nematode Caenorhabditis elegans enables complete delineation of cell lineages throughout development. Despite extensive studies of cell division, cell migration and cell fate differentiation, cell morphology during development has not yet been systematically characterized in any metazoan, including C. elegans.

Promoting Earth-Based Radar Astronomical Observations of the Moon.

Earth-based radar astronomical observations provide information on surface characteristics, orbits, and rotations for a wide variety of solar system objects. Based on compound radio telescopes, both the Chinese VLBI (Very Long Baseline Interferometry) network (CVN) and the Russian VLBI network (Quasar), in cooperation with the Chinese radar transmitters, we present the current ground radar astronomical observations of the moon. The spectrum of the reflected radio signals was obtained and the Doppler frequency shift in bi-static radar mode was measured.

Diagnostic accuracy of multi-slice computed tomography in children with Abernethy malformation.

Background: Abernethy malformation is a rare congenital abnormality. Imaging examination is an important method for the diagnosis. The purpose of this study was to demonstrate manifestations of multi-slice computed tomography (MSCT) in Abernethy malformation and its diagnostic accuracy.

3DMMS: robust 3D Membrane Morphological Segmentation of C. elegans embryo.

Background: Understanding the cellular architecture is a fundamental problem in various biological studies. C. elegans is widely used as a model organism in these studies because of its unique fate determinations.

Observing APOD with the AuScope VLBI Array.

The possibility to observe satellites with the geodetic Very Long Baseline Interferometry (VLBI) technique is vividly discussed in the geodetic community, particularly with regard to future co-location satellite missions. The Chinese APOD-A nano satellite can be considered as a first prototype-suitable for practical observation tests-combining the techniques Satellite Laser Ranging (SLR), Global Navigation Satellite Systems (GNSS) and VLBI on a single platform in a Low Earth Orbit (LEO). Unfortunately, it has hardly been observed by VLBI, so major studies towards actual frame ties could not be performed.

Primitive neuroectodermal tumor originating from the lung: A case report.

Primitive neuroectodermal tumors (PNETs) are small, round cell tumors that may be classified as peripheral or central, based on their site of origin. PNETs often arise in the soft tissue or bone of young adults. Although not common, PNETs have been described in other organs, including the gonads, kidneys, myocardium and pancreas, but rarely in the lungs without chest wall or pleural involvement.

Anti-tumor and immunomodulatory activities of an exopolysaccharide from Rhizopus nigricans on CT26 tumor-bearing mice.

This study was aimed to investigate the anti-tumor and immunomodulatory activities of an exopolysaccharide (EPS) from Rhizopus nigricans. Our results showed EPS could significantly inhibit the tumor growth and increase the immune organs index of CT26 tumor-bearing mice. EPS treatment increased the productions of interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α) levels in serum.

Anti-tumor activity of exopolysaccharide from Rhizopus nigricans Ehrenb on S180 tumor-bearing mice.

In this study, the effect of antitumor and immune activities of extracellular polysaccharides (EPS) from Rhizopus nigricans Ehrenb were investigated using S180 bearing mice. The results revealed that EPS in the concentration range 50-1000 μg/mL can inhibited S180 cell proliferation in a dose dependent manner. EPS at the highest dose of 1000 μg/mL showed significantly antitumor activity against S180 with inhibition rate of 47.

Neuroprotective effect of AG490 in experimental traumatic brain injury of rats.

Background: Traumatic brain injury (TBI) is a major cause of death and disability in children and young adults worldwide. Therefore, we investigated the role of AG490 in regulating brain oedema, expression of CD40 and neurological function after TBI.

Methods: Sprague Dawley rats (n = 240) were randomly divided into a sham operation group, TBI+saline group and TBI+AG490 (JAK/STAT inhibitor) group.

An exopolysaccharide from Trichoderma pseudokoningii and its apoptotic activity on human leukemia K562 cells.

In this study, a novel exopolysaccharide (EPS) was isolated from the fermentation broth of Trichoderma pseudokoningii and its anticancer activities on human leukemia K562 cells were studied. EPS could significantly inhibited K562 cells proliferation in a time- and concentration-dependent manner. Meanwhile, characteristic of apoptosis, including apoptotic morphological features and the apoptosis rate were obtained.

Macrophage immunomodulatory activity of extracellular polysaccharide (PEP) of Antarctic bacterium Pseudoaltermonas sp.S-5.

Antarctic bacteria are a novel source of polysaccharides which might have potential applications as biological response modifiers (BRM). A heteropolysaccharide (PEP) was isolated from the liquid culture broth of the Antarctic bacterium Pseudoaltermonas sp.S-5.