Spatial transcriptome reveals the region-specific genes and pathways regulated by Satb2 in neocortical development.

Background: It is known that the neurodevelopmental disorder associated gene, Satb2, plays important roles in determining the upper layer neuron specification. However, it is not well known how this gene regulates other neocortical regions during the development. It is also lack of comprehensive delineation of its spatially regulatory pathways in neocortical development.

Genomes shed light on the evolution of Begonia, a mega-diverse genus.

Clarifying the evolutionary processes underlying species diversification and adaptation is a key focus of evolutionary biology. Begonia (Begoniaceae) is one of the most species-rich angiosperm genera with c. 2000 species, most of which are shade-adapted.

Development of an inoculation technique for rapidly evaluating maize inbred lines for resistance to stalk rot caused by spp. in the field.

Maize ( L.) stalk rot, caused primarily by the soil-borne fungal pathogen spp., reduces maize quality and yield worldwide.

The hornwort genome and early land plant evolution.

Hornworts, liverworts and mosses are three early diverging clades of land plants, and together comprise the bryophytes. Here, we report the draft genome sequence of the hornwort Anthoceros angustus. Phylogenomic inferences confirm the monophyly of bryophytes, with hornworts sister to liverworts and mosses.

The complete chloroplast genome of (Magnoliaceae), a rare and endangered species of China.

Chiu & Chen is a rare and endangered species endemic to subtropical China. Here we assembled and annotated the complete chloroplast (cp) genome of The chloroplast genome of is 160,076 bp in length and encodes 79 protein-coding genes, 30 transfer RNA (tRNA) genes and four ribosomal RNA (rRNA) genes. The maximum-likelihood (ML) phylogenetic analysis result reveals that is most closely related to .

Colon Ascendens Stent Peritonitis (CASP) Induces Excessive Inflammation and Systemic Metabolic Dysfunction in a Septic Rat Model.

The colon ascendens stent peritonitis (CASP) surgery induces a leakage of gut contents, causing polymicrobial sepsis related to post-operative multiple organ failure and death in surgical patient. To evaluate the effects of CASP on multiple organs, we analyzed the systemic metabolic consequences in liver, kidney, lung, and heart of rats after CASP by employing a combination of metabolomics, clinical chemistry, and biological assays. We found that CASP surgery after 18 h resulted in striking elevations of lipid, amino acids, acetate, choline, PC, and GPC in rat liver together with significant depletion of glucose and glycogen.

[Diagnosis and treatment of abdominal cocoon].

Objective: To study the clinical characteristics and the methods of diagnosis and treatment for abdominal cocoon.

Methods: The clinical data of 9 patients with abdominal cocoon treated from July 2000 to February 2004 were analyzed.

Results: The clinical manifestations included abdominal pain, abdominal distention, nausea, vomiting, partial or complete intestinal obstruction in 4 cases among 9 cases, abdominal mass in 5 cases.

Effect of somatostatin versus octreotide on portal haemodynamics in patients with cirrhosis and portal hypertension.

Objectives: Elevated portal inflow is part of the pathogenesis of portal hypertension in patients with cirrhosis. Vasoactive substances appear to play a primary role in the regulation of portal flow. The aim of this study was to investigate the effects of somatostatin and octreotide on portal pressure and plasma levels of insulin-like growth factor (IGF-1), nitric oxide (NO), endothelin-1 (ET-1) and glucagon (GLU).

Treatment of osteoporosis in men using dehydroepiandrosterone sulfate.

Objective: To study the effect of dehydroepiandrosterone sulfate (DHEAS) treatment of osteoporosis in men with T(BMD) > or = 2.5SD.

Methods: Eighty-six patients were randomly divided into two groups: treatment group (n = 44) and control group (n = 42).