Publications by authors named "Jiande Guo"
Article Synopsis
- Acoustoelectric brain imaging (AEBI) is a cutting-edge technique aimed at mapping brain electrical activity with high precision but faces challenges with human application due to unclear signals related to the medium's electrical conductivity and acoustic properties.
- This study experiments with different levels of conductivity and acoustic distributions, using pig tissues to understand how these factors affect AEBI performance, revealing that higher conductivity improves spatial resolution despite decreasing signal amplitude.
- The research highlights that AEBI's effectiveness is compromised when analyzing through human skulls compared to direct tissue imaging, demonstrating the complex interaction between medium properties and the technology's imaging capability, paving the way for future improvements in neuroimaging.
Transcranial-focused ultrasound (tFUS) has potential for both neuromodulation and neuroimaging. Due to the influence of head tissue, especially the skull, its attenuation is a key issue affecting precise focusing. The objective of the present study was to construct a mathematical model of ultrasound attenuation inclusive of skull thickness.
View Article and Find Full Text PDFObjective: Acoustoelectric Brain Imaging (ABI) is a potential method for mapping brain electrical activity with high spatial resolution (millimeter). To resolve the key issue for eventual realization of ABI, testing that recorded acoustoelectric (AE) signal can be used to decode intrinsic brain electrical activity, the experiment of living rat SSVEP measurement with ABI is implemented.
Method: A 1-MHz ultrasound transducer is focused on the visual cortex of anesthetized rat.