Infection Promotes the Progression of Liver Preneoplasia in BALB/c Mice the Activation and Accumulation of High-Mobility Group Box-1.

It has been documented that () infection is linked to chronic hepatitis and fibrosis in male BALB/c mice. However, the mechanism underlying the mice model of -induced hepatocellular carcinoma is not fully known. In this study, male BALB/c mice were infected with for 3, 6, 12, and 18 months.