Highly selective detection of adenine and guanine by NH-MIL-53(Fe)/CS/MXene nanocomposites with excellent electrochemical performance.

Adenine (A) and guanine (G) are mainly found in deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) and play a crucial role in genetic information transfer and protein synthesis. In this study, NH-MIL-53(Fe)/CS/MXene nanocomposites were prepared for detecting guanine and adenine. With high specific surface area, excellent water dispersion, and numerous active sites, MXene (transition metal carbides, nitrides, and carbonitrides) provides a good platform for loading primitive metal-organic frameworks (MOFs).

l-Cysteine-Terminated Triangular Silver Nanoplates/MXene Nanosheets are Used as Electrochemical Biosensors for Efficiently Detecting 5-Hydroxytryptamine.

5-Hydroxytryptamine (5-HT) is an important neurotransmitter, and its content in the human body is of great significance to human health. In this study, an l-cysteine-terminated triangular silver nanoplate loaded on a MXene (two-dimensional transition metal carbide or nitride) (Tri-AgNP/l-Cys/MXene) electrochemical sensor was used to detect 5-HT. As an electrically active amino acid with a sulfhydryl group, l-cysteine (l-Cys) forms a more stable Ag-S bond with silver nanoparticles, which can selectively substitute trisodium citrate (TSC) in TSC-capped triangular silver nanoplates (Tri-Ag-NP/TSC).

Amino-functionalized Cu metal-organic framework nanosheets as fluorescent probes for detecting TNP.

Here, we report a simple and benign method to successfully fabricate amino-functionalized Cu metal-organic framework (NH-Cu-MOF) nanosheets. After synthesizing CuO nanocubes, they were mixed with organic ligand 2-aminoterephthalic acid (NHBDC) solution at room temperature for 4 hours to form NH-Cu-MOF nanosheets. Interestingly, the prepared NH-Cu-MOF nanosheets have ultra-thin thickness, directional growth characteristics and excellent crystallinity.

[Meta-analysis of internal fixation versus hip replacement in the treatment of trochanteric fractures].

Objective: To compare the efficacy of internal fixation (including PFNA and PFN) versus hip replacement (including FHR or THA) in the treatment of trochanteric fractures in adults.

Methods: Reports of studies using randomized controlled trials (RCT) to compare internal fixationg with hip replacement in the management of intertrochanteric fractures were retrieved (up to January 1, 2013) from the Cochrane Library, PUBMED Data, CNKI (China National Knowledge infrastructure), Elsevier, the Chinese Biomedical Database, Wanfang Data, and manually. Methodological quality of the trials was critically assessed, and relevant data were extracted.