Publications by authors named "Jianbin Cheng"

Specific intestinal metabolites are closely associated with the classification, severity, and necrosis of acute pancreatitis (AP) and provide novel insights for in-depth clinical investigations. In this study, the gut microbiota and metabolites of 49 AP patients at different treatment stages and severities were analysed via 16S rDNA sequencing and untargeted metabolomics to investigate the trends in gut microbiota composition and metabolome profiles observed in patients with severe AP. These findings revealed an imbalance in intestinal flora homeostasis among AP patients characterized by a decrease in probiotics and an increase in opportunistic pathogens, which leads to damage to the intestinal mucosal barrier through reduced short-chain fatty acid (SCFA) secretion and disruption of the intestinal epithelium.

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Article Synopsis
  • MicroRNAs play a crucial role in various biological functions, including the development of giant panda embryos, which experience a unique stage of embryonic diapause during late pregnancy.
  • In a study, researchers identified 120 microRNAs in the plasma of pregnant pandas and found nine that were differentially expressed between early and late pregnancy, particularly noting significant downregulation of miR-25b and miR-47 in late pregnancy.
  • The analysis revealed that these microRNAs target a large number of genes involved in the MAPK and Rap1 signaling pathways, which are essential for processes like cell proliferation and differentiation in embryonic development.
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Objective: This study aimed to explore the application value of three-dimensional (3D) visualization technology in the early surgical repair of bile duct injury during laparoscopic cholecystectomy (LC).

Methods: A retrospective analysis was conducted on the clinical data of 15 patients who underwent early surgical repair of bile duct injury during LC with the assistance of 3D visualization technology at the Hepatobiliary Surgery Department of Ningxia Hui Autonomous Region People's Hospital from January 2019 to December 2022. Postoperative efficacy and long-term follow-up outcomes were summarized.

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Background & Aims: Benign ulcerative colorectal diseases (UCDs) such as ulcerative colitis, Crohn's disease, ischemic colitis, and intestinal tuberculosis share similar phenotypes with different etiologies and treatment strategies. To accurately diagnose closely related diseases like UCDs, we hypothesize that contextual learning is critical in enhancing the ability of the artificial intelligence models to differentiate the subtle differences in lesions amidst the vastly divergent spatial contexts.

Methods: White-light colonoscopy datasets of patients with confirmed UCDs and healthy controls were retrospectively collected.

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Infant call structure should have evolved to elicit maximum maternal attention and investment. Neonates of giant pandas produce three types of vocalizations reported to be vitally important in the context of mother-infant communications. However, how cubs, 0-15 days old, communicate with their mothers to elicit maternal care remains unknown.

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Biochemical recurrence (BCR) is a cause of concern in advanced prostate cancer (PCa). Thus, novel diagnostic biomarkers are required to improve clinical care. However, research on PCa immunotherapy is also scarce.

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Colorectal cancer (CRC) is one of the most common neoplastic diseases worldwide. With a high recurrence rate among all cancers, treatment of CRC only improved a little over the last two decades. The mortality and morbidity rates can be significantly lessened by earlier diagnosis and prompt treatment.

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Neck-shoulder pain syndrome is a commonly-seen disease clinically. Modern medicine has had no better therapy for it yet. Acupuncture and moxibustion have a better therapeutic effect, but improper treatment easily induces protracted course.

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Sjogren's syndrome is one of clinical difficult and complicated diseases and there is no radical treatment for it at present. The authors summarize the thinking of clinical syndrome differentiation and treatment of acupuncture and moxibustion, 4 syndrome-differentiation methods and dredging the Triple Energizer channel, and needling three parts by long-term clinical practice and in combination with clinical study achievements of TCM in recent years, and put the important point of treatment on the Triple Energizer, with the points on the Triple Energizer channel as main points, combined with the points with functions of regulating functional activity of qi and regulating visceral functions, attaining better results. This provides a new method for acupuncture and moxibustion treatment of Sjogren's Syndrome.

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Synopsis of recent research by authors named "Jianbin Cheng"

  • - Jianbin Cheng's recent research explores the intricate relationship between intestinal microflora and metabolites in the progression of acute pancreatitis, revealing significant alterations in gut microbiota composition associated with the condition, which may impact clinical approaches to treatment.
  • - His work also investigates the expression profiles of microRNAs in the plasma exosomes of late pregnant giant pandas, contributing to the understanding of reproductive biology and developmental processes in this species, particularly during embryonic diapause.
  • - Additionally, Cheng implements advanced three-dimensional visualization technology in the surgical repair of bile duct injuries, demonstrating improved surgical outcomes in patients, and enhances the diagnostic capabilities for benign ulcerative colorectal diseases using artificial intelligence methodologies.