Semi-Organic Artificial Photosynthetic System with Engineered Phenoxazinone Derivatives for Photocatalytic Hydrogen Production with Broadened Near-Infrared Light Harvesting.

Natural photosynthetic systems utilize complex pigment-protein assemblies for light harvesting across a broad spectral range from UV to near-infrared, enabling efficient photogeneration and charge separation. Conventional photocatalysts, however, primarily absorb UV (<380 nm) and visible light (380-780 nm), resulting in suboptimal spectral utilization. This study introduces a semi-organic artificial photosynthetic system that integrates molecularly engineered phenoxazinone derivatives with H-doped rutile TiO (H-TiO) nanorods.

Bibliometric analysis and research progress on hydrogen peroxide and persulfate oxidation processes in the remediation of actual oil-contaminated soil.

Oil pollution poses significant harm to both the ecological environment and human health. The primary sources of oil pollutants in soil are leaks that occur during the extraction, transportation, and production phases. In the face of the severe situation of global soil pollution, chemical oxidation technology has shown potential in the remediation of oil-contaminated soil.

Recent Advances in Strategies to Enhance Photodynamic and Photothermal Therapy Performance of Single-Component Organic Phototherapeutic Agents.

Photodynamic therapy (PDT) and photothermal therapy (PTT) have emerged as promising treatment options, showcasing immense potential in addressing both oncologic and nononcologic diseases. Single-component organic phototherapeutic agents (SCOPAs) offer advantages compared to inorganic or multicomponent nanomedicine, including better biosafety, lower toxicity, simpler synthesis, and enhanced reproducibility. Nonetheless, how to further improve the therapeutic effectiveness of SCOPAs remains a challenging research area.

Glutathione-Driven Disassembly of Planar Organic Phototherapeutic Agents to Enhance Photodynamic-Photothermal Therapy Performance for Nasopharyngeal Carcinoma.

The self-assembly of hydrophobic organic phototherapeutic agents (OPTAs) with expansive planar structures into nanoparticles (NPs) represents a pivotal strategy to bolster their biocompatibility. However, the tight molecular packing within these NPs significantly influences the generation of reactive oxygen species (ROS) and the photothermal conversion efficiency (PCE), posing a substantial hurdle to elevating the efficacy of photodynamic therapy (PDT) and photothermal therapy (PTT) for such NPs. In this article, three OPTAs by donor engineering are synthesized.

Configuration-Mediated Efficient Non-Radiative Transition for R848-Assisted Photothermal Immunotherapy to Inhibit Tumor Growth and Metastasis by An In Situ Tumor Vaccine Strategy.

Cancer metastasis remains a critical factor contributing to the current limitations in cancer treatment. Photothermal immunotherapy has emerged as a safe and potent therapeutic approach, demonstrating the capability to suppress tumor growth and metastasis. While researchers have extensively investigated various structural modifications to enhance photothermal conversion performance, the influence of molecular configuration has received comparatively limited attention.

Chemical Regulation of Fluorescence Lifetime.

Fluorescence lifetime has significant applications in the field of fluorescence microscopy. Effective modulation of fluorescence lifetime can be achieved by controlling the radiative versus nonradiative processes of fluorophores. In this review, we systematically analyze and summarize chemical approaches that achieve fluorescence lifetime modulation for three different types of fluorophores, including small molecules, quantum dots, and metal complexes.

Efficient sulfur accumulation in biological desulfurisation and denitrification induced by microbial and chemical interactions.

Efficient accumulation of sulfur from simultaneous desulfurisation denitrification process can achieve high economic and environmental benefits. This work aims to study the effect of product accumulation on elemental sulfur production and understand its potential mechanism. The addition of the intermediate product thiosulfate and the final product sulfate during the reaction led to an increase in the production of biological elemental sulfur ().

Kilowatt-level supercontinuum generation employing a homemade taper-shaped ytterbium-doped fiber amplifier.

A simple generation method of high-power supercontinuum (SC) based on a homemade long ytterbium-doped taper fiber (T-YDF) amplifier has been demonstrated experimentally and analyzed in this work. The power and spectra of the obtained SC are made adjustable by changing the seed pulse repetition rates. Under a 7.

Labeling selectivity of lipid droplets fluorescent probes: Twisted intramolecular charge transfer (TICT) vs intramolecular charge transfer (ICT).

Fluorescence imaging technology is a versatile and essential tool in the field of biomedical research. To obtain excellent imaging results, the precise labeling of fluorescent probes is an important prerequisite. Nevertheless, the labeling selectivity of most fluorescent probes is not satisfactory, new design concepts are desperately needed.

Efficient and sustained inhibition of ammonia nitrogen release from sediment in water by microbial self-aggregation zeolite layer.

Despite global efforts to manage water eutrophication, the continual release of ammonia nitrogen from sediments maintains the eutrophic state of water bodies, presenting serious challenges to the management. In order to find an efficient method for sediment remediation, the experiment of using signal molecules to enhance the adhesion of microorganisms on zeolite was carried out. Five different zeolitic ammonium adsorptions were examined using two different signal molecules, N-(3-oxohexanoyl)-L-homoserine lactone (OHHL) and N-(β-ketocaproyl)-DL-homoserine lactone (C6), to enhance microbial attachment on two types of zeolites.

Self-Healing, Laminated, and Low Resistance NH Sensor Based on 6,6',6″-(Nitrilotris(benzene-4,1-diyl))tris(5-phenylpyrazine-2,3-dicarbonitrile) Sensing Material Operating at Room Temperature.

With the rapid development of the concept of the Internet of Things (IoT), gas sensors with the function of simulating the human sense of smell became irreplaceable as a key element. Among them, ammonia (NH) sensors played an important role in respiration tests, environmental monitoring, safety, and other fields. However, the fabrication of the high-performance device with high stability and resistance to mechanical damages was still a challenge.

Ultrabright organic fluorescent probe for quantifying the dynamics of cytosolic/nuclear lipid droplets.

Lipid droplets (LDs) are extremely active organelles that play a crucial role in energy metabolism, membrane formation, and the production of lipid-derived signaling molecules by regulating lipid storage and release. Nevertheless, directly limited by the lack of superior fluorescent probes, studies of LDs dynamic motion velocity have been rarely reported, especially for nuclear LDs. Herein, a novel organic fluorescent probe Lipi-Bright has been rationally developed based on bridged cyclization of distyrylbenzene.

Fast degradation of macro alkanes through activating indigenous bacteria using biosurfactants produced by Burkholderia sp.

Soil bacteria that produce biosurfactants can use total petroleum hydrocarbons (TPHs) as a carbon source. This study demonstrated that biosurfactants produced by Burkholderia sp. enhanced the recovery and synergism of soil microbial community, resulting in fast degradation of macro alkanes.

Super-resolution dynamic tracking of cellular lipid droplets employing with a photostable deep red fluorogenic probe.

Lipid droplets (LDs) are critical organelles involved in many physiological processes in eukaryotic cells. To visualize and study LDs, particular the small/nascent LDs, the emerging super-resolution fluorescence imaging techniques with nanoscale resolution would be much more powerful in comparison to the conventional confocal/wide-field imaging techniques. However, directly limited by the availability of advanced LDs probes, super-resolution fluorescence imaging of LDs is a practically challenging task.

Construction of a red emission fluorescent probe for selectively detection of cysteine in living cells.

Cysteine (Cys) is a vital amino acid in the body, and its abnormal expression level is associated with many diseases. In this study, a novel fluorescent probe ACHB was synthesized, showing high selectivity, anti-interference ability and achieving accurate detection of cysteine. Different from most previous off-on probes, ACHB showed an on-off fluorescence response to Cys.

Highly Efficient Red/NIR-Emissive Fluorescent Probe with Polarity-Sensitive Character for Visualizing Cellular Lipid Droplets and Determining Their Polarity.

Lipid droplets (LDs), which are ubiquitous organelles existing in almost all eukaryotic cells, have attracted a lot of attention in the field of cell biology over the last decade. For the biological study of LDs via fluorescence imaging, the superior LD fluorescent probes with environmental polarity-sensitive character are highly desired and powerful but are very scarce. Herein, we have newly developed such a kind of fluorescent probe named LDs-Red which enables us to visualize LDs and to further reveal their polarity information.

Molecular Conformation Engineering To Achieve Longer and Brighter Deep Red/Near-Infrared Emission in Crystalline State.

A series of molecules - containing the same fluorophore and different alkyl chains are synthesized to reveal the significant effect of molecular conformations on the emission properties. In crystalline state, molecules - exhibit strong orange emissions with maxima (λ) of about 600 nm and quantum yields (Φ) of around 60%, while molecules and display much longer emissions to the deep red/near-infrared (NIR) region as well as even higher efficiencies (λ = 693 nm, Φ = 73% for ; λ = 654 nm, Φ = 93% for ). The largely red-shifted emissions of and as well as the significantly improved Φ are very unusual.

STED Nanoscopy Imaging of Cellular Lipid Droplets Employing a Superior Organic Fluorescent Probe.

Lipid droplets (LDs) are spherical organelles that participate in numerous biological processes. In order to visualize LDs on the nanoscale, nanoscopy fluorescence imaging is considered as the most attractive technique but is substantially limited by the characteristics of fluorescent probes. Thus, the development of a superior fluorescent probe that is capable of nanoscopy fluorescence imaging has attracted enormous attention.

Modal perspective on geometric parametric instability sidebands in graded-index multimode fibers.

In this paper, we investigated the geometric parametric instability (GPI) in graded-index multimode fibers through the multimode generalized nonlinear Schrödinger equation. Our results clearly and intuitively indicate that the generations of GPI sidebands are nearly synchronous in the spectrums of all modes, and the shapes of these spectrums are nearly the same. The numerical results show that the energies of the GPI sidebands come from the pump sideband, and these sidebands are carried by similar spatial beam profiles due to the similar modal components.

Detection of Carboxylesterase 1 and Chlorpyrifos with ZIF-8 Metal-Organic Frameworks Using a Red Emission BODIPY-Based Probe.

In this work, a red emission fluorescent probe CBZ-BOD@zeolitic imidazolate framework-8 (ZIF-8) was fabricated based on metal-organic frameworks (MOFs) for detecting carboxylesterase 1 (CES1). The small molecule probe CBZ-BOD was first synthesized and then used to prepare the functionalized MOF material. ZIF-8 was chosen as an encapsulation shell to improve the detection properties of CBZ-BOD.

Construction of a red emission fluorescent protein chromophore-based probe for detection of carboxylesterase 1 and carbamate pesticide in culture cells.

Designing fluorescent probe for detecting carboxylesterase 1 is remains challenging. Herein, a red emission human carboxylesterase 1 (CES1) probe (CAE-FP) was synthesized based on fluorescent protein chromophore. Probe CAE-FP can specific detect human CES1 with high selectively.

Lysosome targeting metal-organic framework probe LysFP@ZIF-8 for highly sensitive quantification of carboxylesterase 1 and organophosphates in living cells.

Herein, a lysosomal targeting LysFP@ZIF-8 metal-organic framework (MOF) was fabricated using fluorescent protein chromophore-based probe (LysFP) for selectively detection of carboxylesterase 1 (CES1) in living cells. Unlike the regular small molecule fluorescent probes, LysFP@ZIF-8 showed wide range pH tolerabiligy, high selectivity and sensitivity to CES1 in bio-samples, and was successfully applied to achieve the visual monitoring of CES1 activity in living cells. Low detection limit and high fluorescence quantum yield was calculated as 79 ng/mL and 0.