Publications by authors named "JianTao Liu"

Combining photothermal and chemotherapy using single nanoplatform is an emerging direction in cancer nanomedicine. Herein, a magnetic field (MF) induced combination of chemo/photothermal therapy is demonstrated using FeO@mSiO@Au core@shell@satellites nanoparticles (NPs) loaded with chemotherapeutic drug doxorubicin (DOX), both and An application of an external MF to the NPs dispersion causes magnetophoretic movement and aggregation of the NPs. While the synthesized NPs only slightly absorb light at ∼800 nm, their aggregation results in a significant near infrared (NIR) absorption associated with plasmon resonance coupling between the Au satellites in the NPs aggregates.

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  • - The multicore fiber amplifier is essential for advanced spatial division multiplexing (SDM) communication, but it has more complex challenges than traditional single-core systems, prompting the search for a more efficient solution.
  • - An innovative triple cladding 13-core Er/Yb co-doped microstructured fiber (13CEYDMOF) is proposed to balance performance factors like efficiency and cost, featuring unique peanut-shaped air holes that improve excitation and reduce fiber size.
  • - Experimental results show that the 13CEYDMOF achieved impressive performance metrics, including an average gain of 23.8 dB and a low noise figure, making it suitable for transmitting 13 spatial channels effectively in the telecommunication band.
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Supramolecular protein assemblies have been used as intelligent drug delivery systems that can encapsulate drugs and transport them to specific tissues or cells. However, the known methods for designing supramolecular protein assemblies for transportation across the blood-brain barrier (BBB) remain challenging and inefficient. Herein, we report that the supramolecular recombinant-protein-based strategy enables the biosynthesis and production of a supramolecular protein assembly that is intrinsically capable of crossing the BBB.

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Continuous exploitation in mining areas damages the surrounding environment and has various severe geological impacts. Hence, long-term monitoring of mining areas is crucial to reducing these impacts. Differential interferometric synthetic aperture radar (D-InSAR) is widely applied to monitor the subsidence in mining areas, but it cannot obtain accurate large-gradient subsidence result in the centre of the subsidence basin in mining areas due to the de-coherence phenomenon.

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  • - The study focuses on improving fault diagnosis methods for permanent magnet synchronous motors (PMSMs), which are crucial in industrial applications, particularly in challenging environments.
  • - An intelligent approach combining continuous wavelet transform (CWT) and convolutional neural networks (CNNs) is proposed to analyze and classify the motor's fault conditions, specifically inter-turn short-circuits and demagnetization.
  • - The results show exceptional diagnosis accuracy of over 98.6% for various severities of these faults, utilizing feature extraction visualized through t-distributed stochastic neighbor embedding (t-SNE).
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Fluorescence imaging (FI) employing near-infrared (NIR) light within the range of ~750-1350 nm enables biomedical imaging several millimeters beneath the tissue surface. More recent investigations into the short-wave IR (SWIR) transparency windows between ~1550-1870 and 2100-2300 nm highlight their superior capabilities. This research presents a comparison of IR-FI of PbS quantum dots, emitting at 990, 1310, and 1580 nm, through the mouse scalp skin, skull, and brain.

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Resource utilization of tail vegetables has raised increasing concerns in the modern agriculture. However, the effect and related mechanisms of flue-cured tobacco leaves on the product quality, phytotoxicity and bacterially-mediated nitrogen (N) transformation process of tail vegetable composting were poorly understood. Amendments of high-dosed (5% and 10% w/w) tobacco leaves into the compost accelerated the heating process, prolonged the time of thermophilic stage, increased the peak temperature, thereby improving maturity and shortening composting duration.

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The application of biochar in degraded farmland improves soil productivity while achieving the recycling of agricultural waste. The collapse of the physical structure of coastal saline soils will greatly reduce the carbon sequestration potential of biochar. Phosphorus- and magnesium-modified biochar greatly improve the stability of biochar, which endows them with the potential to greatly improve the organic carbon pool of coastal saline soil.

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Objective: To investigate the clinical effect of anterior cervical discectomy and fusion (ACDF) in the treatment of cervical spondylosis of vertebral artery type(CSA).

Methods: The clinical data of 42 patients with CSA from January 2020 to January 2022 were retrospectively analyzed. There were 25 males and 17 females, aged from 30 to 74 years old with an average of (53.

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Lowing blood lipid levels with probiotics has good application prospects. This study aimed to isolate probiotics with hypolipidemic efficacy from homemade na dish and investigate their mechanism of action. experiments were conducted to determine the cholesterol-lowering ability of five isolates, with results showing that N4 exhibited a high cholesterol-lowering rate of 50.

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Background: With the advent of artificial intelligence technology, machine learning algorithms have been widely used in the area of disease prediction.

Objective: Cardiovascular disease (CVD) seriously jeopardizes human health worldwide, thereby needing the establishment of an effective CVD prediction model that can be of great significance for controlling the risk of the disease and safeguarding the physical and mental health of the population.

Methods: Considering the UCI heart disease dataset as an example, initially, a single machine learning prediction model was constructed.

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: Alzheimer's disease (AD) exerts tremendous pressure on families and society due to its unknown etiology and lack of effective treatment options. Our previous study had shown that Se-methylselenocysteine (SMC) improved the cognition and synaptic plasticity of triple-transgenic AD (3 × Tg-AD) mice and alleviated the related pathological indicators. We are dedicated to investigating the therapeutic effects and molecular mechanisms of SMC on mitochondrial function in 3 × Tg-AD mice.

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  • A mobile artificial lumbar complex (MALC) was developed for reconstructing goat spines after subtotal lumbar resection and assessed for stability and motor function post-surgery.
  • The study involved 18 male boer goats divided into three groups: control, fusion, and non-fusion, with varying surgical interventions and the use of 3D printed MALC.
  • Results indicated successful positioning of the MALC without complications and no significant differences in range of motion for the lumbar intervertebral spaces after six months.
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In vivo near infrared (NIR) fluorescence imaging and laser speckle contrast imaging (LSCI) are emerging optical bioimaging modalities, which can provide information on blood vessels morphology, volume and the blood flow velocity. Optical tissue clearing (OTC) technique addresses a light scattering problem in optical bioimaging, which is imperative for the transcranial brain imaging. Herein, we report an approach combining NIR fluorescence and LSC microscopy imaging with OTC.

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Bone implants for different body parts require varying mechanical properties, dimensions, and biodegradability rates. Currently, it is still challenging to produce artificial bones with perfect compatibility with human bones. In this study, a silk-fabric reinforced silk material (SFS) composed of pure silk with exceptional biocompatibility, osteogenesis, and biodegradability is reported, and demonstrates its outstanding performance as a bone implant material.

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Intravital luminescence imaging in the second near-infrared window (NIR-II) enables noninvasive deep-tissue imaging with high spatiotemporal resolution of live mammals because of the properties of suppressed light scattering and diminished autofluorescence in the long-wavelength region. Herein, we present the synthesis of a downconversion luminescence rare-earth nanocrystal with a core-shell-shell structure (NaYF@NaYbF:Er,Ce@NaYF:Ca). The structure efficiently maximized the doping concentration of the sensitizers and increased Er luminescence while preventing cross relaxation.

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Heat stress in chickens caused by high temperatures in summer is a serious issue faced by the poultry industry globally, which reduces product quality. The aim of this study is to investigate the role of resveratrol in alleviating heat stress injury and inflammatory response of jejunal mucosa in black-boned chickens through TLR4/MAPK signaling pathway. In total, 240 black-boned chickens (28-day old) were randomly divided into 4 treatment groups as follows.

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In limited land space, improving the construction of infrastructure with ecological services can help to achieve the goal of promoting land use eco-efficiency (LUEE). In view of this, this study constructed interactive coordination relationship model of green infrastructure (GI) and LUEE that involves entropy method model, super-efficiency slack-based measure (SBM) model with undesirable outputs, and coupling coordination degree model. The interactive coordination relationship model can help to study and reveal the mechanisms of interaction and the coordination relationship between GI and LUEE from a land benefit and ecological perspective.

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There are various internal fixation methods in treating lumbosacral spinal tuberculosis. The study compared the stability and stress distribution in surrounding tissues/implants, such as discs, endplates and screw-rod internal fixation system, etc. when applying three different lumbar internal fixation methods to treat lumbosacral spinal tuberculosis.

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  • Soft strain gauges, made from flexible materials, solve problems related to traditional rigid gauges, like poor sensing range and fracture issues.
  • A new hybrid material made from gel and elastomer shows impressive durability and sensitivity, capable of detecting tiny strains and human motion accurately.
  • By using advanced patterning techniques and machine learning, this technology can create intelligent systems to monitor human movements, paving the way for improved wearable devices.
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  • A genome-wide association study (GWAS) was conducted on Longyan Shan-ma ducks to identify genes related to primary feather color using genotyping-by-sequencing (GBS) technology.
  • Seven significant single nucleotide polymorphisms (SNPs) were found within specific genes, indicating a strong association with feather color traits.
  • The study identified key genes involved in pigmentation and follicle development, suggesting potential genetic mechanisms influencing feather color in these ducks.
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The bacteria Clostridium cellulolyticum is a promising candidate for consolidated bioprocessing (CBP). However, genetic engineering is necessary to improve this organism's cellulose degradation and bioconversion efficiencies to meet standard industrial requirements. In this study, CRISPR-Cas9n was used to integrate an efficient β-glucosidase into the genome of C.

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Ti6Al4V titanium alloy is widely used in producing orthopedic and maxillofacial implants, but drawbacks include high elastic modulus, poor osseointegration performance, and toxic elements. A new medical titanium alloy material with better comprehensive performance is urgently needed in the clinic. Ti10Mo6Zr4Sn3Nb titanium alloy (referred to as Ti-B12) is a unique medical titanium alloy material developed by us.

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Context: Although Tongguan capsule (TGC) is used in the treatment of coronary atherosclerotic disease, the exact mechanism remains unclear.

Objective: Network pharmacology and experimental validation were applied to examine the mechanism of TGC for treating myocardial ischemia-reperfusion injury (MIRI).

Materials And Methods: The components and candidate targets were searched based on various databases such as TCMSP, TCMID, BATMAN-TCM.

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  • Natural biological tissues, like ligaments, have a unique structure that allows them to maintain high water content while being strong and flexible.
  • Conventional hydrogels struggle to match this strength and fatigue resistance, especially at high water contents.
  • A new strategy using freeze-casting and salting-out techniques creates a strong, flexible hydrogel with 79.5% water content, enhanced by carbon nanotubes, achieving high strength (4.5 MPa) and excellent durability for biomedical use.
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