Corrigendum: RNA interference of in response to Aspergillus flavus partitivirus 1 infection.

[This corrects the article DOI: 10.3389/fmicb.2023.

The Circadian Rhythm Regulates the Hepato-ovarian Axis Linking Polycystic Ovary Syndrome and Non-alcoholic Fatty Liver Disease.

This study aimed to identify shared gene expression related to circadian rhythm disruption in polycystic ovary syndrome (PCOS) and non-alcoholic fatty liver disease (NAFLD) to discover common diagnostic biomarkers. Visceral fat RNA samples were collected from 12 PCOS and 14 non-PCOS patients, a sample size representing the clinical situation and sufficient to capture PCOS gene expression profiles. Along with liver transcriptome profiles from NAFLD patients, these data were analyzed to identify crosstalk circadian rhythm-related genes (CRRGs) between the diseases.

Dual-Modal Memory Enabled by a Single Vertical N-Type Organic Artificial Synapse for Neuromorphic Computing.

Complementary neural network circuits combining multifunctional high-performance p-type with n-type organic artificial synapses satisfy sophisticated applications such as image cognition and prosthesis control. However, implementing the dual-modal memory features that are both volatile and nonvolatile in a synaptic transistor is challenging. Herein, for the first time, we propose a single vertical n-type organic synaptic transistor (VNOST) with a novel polymeric organic mixed ionic-electronic conductor as the core channel material to achieve dual-modal synaptic learning/memory behaviors at different operating current densities via the formation of an electric double layer and the reversible ion doping.

Associations between serum cytokine levels and postmenopausal depression in postmenopausal women with and without menopause hormone therapy.

Background: The etiology of depression involves many biological and environmental factors, among which the inflammatory process is an important contributor. However, the role of pro-inflammatory cytokines in postmenopausal depression is unclear. Therefore, we aimed to explore the association between the serum concentrations of four pro-inflammatory cytokines (IL-1β, IL-6, IL-18, and TNF-α) and depressive symptoms in postmenopausal women who had been receiving menopause hormone therapy (MHT) for at least 6 months and postmenopausal women who had not received MHT.

Sustainable and smart rail transit based on advanced self-powered sensing technology.

As rail transit continues to develop, expanding railway networks increase the demand for sustainable energy supply and intelligent infrastructure management. In recent years, advanced rail self-powered technology has rapidly progressed toward artificial intelligence and the internet of things (AIoT). This review primarily discusses the self-powered and self-sensing systems in rail transit, analyzing their current characteristics and innovative potentials in different scenarios.

MiR-204 regulates autophagy and cell viability by targeting BDNF and inhibiting the NTRK2-dependent PI3K/Akt/mTOR pathway in a human granulosa cell line exposed to bisphenol A.

Bisphenol A (BPA) is a widespread endocrine disruptor that mimics estrogen. The accumulation of BPA within the human body has been shown to be detrimental to ovarian function. However, few studies have focused on the specific mechanisms by which it causes harm to granulosa cells (GCs), pivotal ovarian cells that are responsible for the growth and function of oocytes.

Proteomic Analysis Reveals Major Proteins and Pathways That Mediate the Effect of 17-β-Estradiol in Cell Division and Apoptosis in Breast Cancer MCF7 Cells.

Despite extensive research, the genes/proteins and pathways responsible for the physiological effects of estrogen remain elusive. In this study, we determined the effect of estrogen on global protein expression in breast cancer MCF7 cells using a proteomic method. The expression of 77 cytosolic, 74 nuclear, and 81 membrane/organelle proteins was significantly altered by 17-β-estradiol (E2).

Parasitic Leiomyoma at Laparoscopic Trocar Site: A Report of 2 Cases.

BACKGROUND Parasitic leiomyoma refers to leiomyomas outside the uterus, with a prevalence of 0.07%. Patients are initially asymptomatic and may later develop abdominal pain and abdominal distension.

Multi-omic analyses identified SFRP4 as a novel biomarker in abnormal uterine bleeding with ovulatory dysfunction.

The goal of the study was to explore the mechanism underlying the progression from abnormal uterine bleeding with ovulatory dysfunction (AUB-O) to AUB with atypical hyperplasia/malignancy (AUB-M). AUB-O, AUB-M and control endometrial tissues were subjected to multi-omic analyses to identify biomarkers. Differentially expressed genes (DEGs) and differentially expressed proteins (DEPs), including SFRP4, between the AUB-O and AUB-M groups were identified.

Vaginal microbiota, menopause, and the use of menopausal hormone therapy: a cross-sectional, pilot study in Chinese women.

Objective: To compare the vaginal microbiota of premenopausal and postmenopausal women and postmenopausal women undergoing menopausal hormone therapy (MHT) and examine the association between vaginal microbiota and genitourinary syndrome of menopause (GSM).

Methods: This cross-sectional study classified 94 women aged 40 to 60 years into three groups: premenopausal (Pre, n = 32), postmenopausal (Post, n = 30), and postmenopausal women who received MHT orally (Post + MHT, n = 32). Neither the Pre nor the Post group received hormone therapy within the past 6 months.

A robust, high-temperature-resistant, protective cellulose gel enabled by multiscale structural engineering.

Given the escalating environmental and safety concerns, friendly protective materials with exceptional mechanical properties, biodegradability, and insensitivity to high temperature have received more and more attention. Here, we report a robust cellulosic gel through the multi-scale integration of cellulose molecular skeleton, nano-reinforced diatomite, and in situ polymerized polyacrylamide molecule. The bottom-up yet cross-scale approach facilitates the formation of cellulosic gel characterized by a highly interconnected hydrogen bond network and nano-enhanced domain, resulting in a tensile strength of up to 13.

EAIA: An Efficient and Anonymous Identity-Authentication Scheme in 5G-V2V.

Vehicle Ad-hoc Networks (VANETs) have experienced significant development in recent years, playing a crucial role in enhancing the driving experience by enabling safer and more efficient inter-vehicle interactions through information exchange. Vehicle-to-Vehicle (V2V) communication is particularly vital as it not only helps to prevent collisions and improve traffic efficiency but also provides essential situational awareness to drivers or autonomous driving systems. Communication is typically supported by roadside units (RSUs); however, in practical applications, vehicles may exceed the communication range of RSUs, thus exposing them to various malicious attacks.

Supervised Group-Based Exercise for Preventing Falls Among Older Adults in the Community: A Systematic Review and Meta-Analysis.

Background: Supervised group exercise may have greater health benefits than no exercise or exercise alone.

Purpose: The purpose of this systematic review and meta-analysis was to investigate the effectiveness of supervised group-based exercise on the risk of falls among community-dwelling older adults compared to no exercise or exercise alone.

Methods: Four databases were searched up to March 1, 2024 for eligible randomized controlled trials.

Proteomic analysis reveals the dominant effect of ipomoeassin F on the synthesis of membrane and secretory proteins in triple-negative breast cancer cells.

Ipomoeassin F (Ipom-F) is a natural compound with embedded carbohydrates that exhibits a potent cytotoxic effect on triple-negative breast cancer (TNBC) cells. The mechanism behind this selective potency remains unclear. To elucidate this mechanism, we analyzed the proteome profiles of the TNBC MDA-MB-231 cells after exposure to Ipom-F at different time points and increasing doses using a quantitative proteomic method.

Application of metagenomic next-generation sequencing for rapid molecular identification in spinal infection diagnosis.

Objective: This study aimed to determine the sensitivity and specificity of metagenomic next-generation sequencing (mNGS) for detecting pathogens in spinal infections and to identify the differences in the diagnostic performance between mNGS and targeted next-generation sequencing (tNGS).

Methods: A total of 76 consecutive patients with suspected spinal infections who underwent mNGS, culture, and histopathological examinations were retrospectively studied. The final diagnosis of the patient was determined by combining the clinical treatment results, pathological examinations, imaging changes and laboratory indicators.

Delayed postoperative neurological deficits from scoliosis correction: a case series and systematic review on clinical characteristics, treatment, prognosis, and recovery.

Objective: This study was designed to investigate the clinical features, treatment modalities, and risk factors influencing neurological recovery in patients who underwent scoliosis correction with delayed postoperative neurological deficit (DPND).

Methods: Three patients with DPND were identified from 2 central databases for descriptive analysis. Furthermore, all DPND cases were retrieved from the PubMed and Embase databases.

Isolation, characterization and therapeutic evaluation of a new Acinetobacter virus Abgy202141 lysing .

is an opportunistic pathogen that easily resists currently available antibiotics. Phages are considered alternative therapeutic agents to conventional antibiotics for the treatment of multidrug-resistant bacteria. We isolated an Acinetobacter virus Abgy202141 from underground sewage in a residential area of Guiyang City in China.

Detoxification and Activating Blood Circulation Decoction Promotes Reendothelialization of Damaged Blood Vessels via VEGF Signaling Pathway Activation by miRNA-126.

The occurrence of in-stent restenosis (ISR) poses a significant challenge for percutaneous coronary intervention (PCI). Thus, the promotion of vascular reendothelialization is essential to inhibit endothelial proliferation. In this study, we clarified the mechanism by which Detoxification and Activating Blood Circulation Decoction (DABCD) promotes vascular reendothelialization to avoid ISR by miRNA-126-mediated modulation of the vascular endothelial growth factor (VEGF) signaling pathway.

A Blockchain-Assisted Security Protocol for Group Handover of MTC Devices in 5G Wireless Networks.

In the realm of the fifth-generation (5G) wireless cellular networks, renowned for their dense connectivity, there lies a substantial facilitation of a myriad of Internet of Things (IoT) applications, which can be supported by the massive machine-type communication (MTC) technique, a fundamental communication framework. In some scenarios, a large number of machine-type communication devices (MTCD) may simultaneously enter the communication coverage of a target base station. However, the current handover mechanism specified by the 3rd Generation Partnership Project (3GPP) Release 16 incurs high signaling overhead within the access and core networks, which may have negative impacts on network efficiency.

The relationship between caffeine and its metabolites and bone mineral density in postmenopausal women: a cross-sectional analysis from the NHANES database.

We aim to explore the association between caffeine and its metabolites and bone mineral density (BMD) in postmenopausal women. Data of 4286 postmenopausal women were extracted from the National Health and Nutrition Examination Survey (NHANES) database in 2009-14 in this cross-sectional study. Weighted linear regression and stepwise regression analyses were used to screen the covariates.