Publications by authors named "JianFen Zhang"

Article Synopsis
  • * A total of 78 participants provided stool samples, and tests revealed a 98.7% detection rate of various microplastics, with an average concentration of 54.7 μg/g, differing significantly among the three cities.
  • * Results indicated that higher consumption of takeaway and reheated foods, as well as drinking bottled water, correlated with increased microplastic concentrations in stools, highlighting lifestyle factors that contribute to microplastic exposure.
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The study aimed to explore the associations between water intake and body composition and differences of body composition in different water itake and hydration statuses among young male athletes. A cross-sectional study was conducted among 111 young male athletes in Beijing, China. Total drinking fluids (TDF) and water from food were assessed using a 7-day, 24-h fluid intake record questionnaire and the duplicate portion method, respectively.

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Objective: This study aimed to systematically assess the total environmental exposure to microplastics and determine the internal exposure levels in the human body.

Methods: A total of 26 young college students were recruited. Exposure scenario estimation methods were used to establish evaluation models.

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Article Synopsis
  • - Fractures are a major concern for children's health in China, but there's a gap in large-scale community research focusing on this issue.
  • - A recent study found that 6.93% of Chinese children aged 6-17 have experienced fractures, with higher rates in boys (8.13%) versus girls (5.71%) and in rural areas (7.22%) compared to urban ones (6.62%), mainly affecting the upper limbs.
  • - To improve public health, it's important to raise awareness about fracture prevention, especially for boys and children in rural areas; recommendations include investing in educational programs and promoting safe exercise and nutrition.
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Background: Evidence on the association between environmental factors and fluid intake behavior remains limited. The current study aims to explore seasonal variations in fluid intake behaviors among young adults in China.

Methods: A prospective cohort of 79 healthy young adults (43 males and 36 females) aged 19-21 in Hebei, China, was assessed for fluid intake behaviors for four seasons.

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Background: Water is vital for humans' survival and general health, which is involved in various metabolic activities.

Objectives: The aim of this study was to investigate the variation in urine metabolome and associated metabolic pathways among people with different hydration states.

Methods: A metabolomic analysis was conducted using 24-h urine samples collected during a cross-sectional study on fluid intake behavior from December 9 to 11, 2021, in Hebei, China.

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A novel acidophilic GH5 β-1,4-endoglucanase (TaCel12) from Trichoderma asperellum ND-1 was efficiently expressed in Pichia pastoris (a 1.5-fold increase). Deglycosylated TaCel12 migrated as a single band (26.

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Background: Fluid intake in the elderly may influence urination behaviors and further influence their health status. This study investigated the behaviors of fluid intake, urination and their relationships among the elderly in China.

Methods: Stratified random sampling was used to recruit the elderly participants who met the inclusion criteria from five cities in China.

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Mannan, a highly abundant and cost-effective natural resource, holds great potential for the generation of high-value compounds such as bioactive polysaccharides and biofuels. In this study, we successfully enhanced the expression of constructed GH5 β-mannanase (TaMan5) from ND-1 by employing propeptide in . By replacing the α-factor with propeptide (MGNRALNSMKFFKSQALALLAATSAVA), TaMan5 activity was significantly increased from 67.

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Background And Objectives: To explore the relationship between water intake, hydration biomarkers and physical activity of young male athletes.

Methods And Study Design: A 7-day cross-sectional study was conducted among 45 male athletes aged 18-25 years in Beijing, China. Total drinking fluids (TDF) was obtained using 7-day 24-h fluid intake questionnaire.

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Studies on the water intake of athletes in daily life are insufficient. The objective was to determine the water intake and hydration status among physically active male young adults. In this cross-sectional studies study, 111 physically active male young adults were recruited.

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The effects of dehydration and rehydration on brain regional density and homogeneity are unknown and have been infrequently studied. In this pilot self-control study, twelve participants aged 18-25 years were recruited and the brain was scanned using magnetic resonance imaging for three tests under different hydration statuses. In three tests, urine osmolality was determined to assess hydration status.

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Acidophilic β-xylanases have attracted considerable attention due to their excellent activity under extreme acidic environments and potential industrial utilizations. In this study, a novel β-xylanase gene () of glycoside hydrolase family 11, was cloned from ND-1 and efficiently expressed in (a 2.0-fold increase).

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Unlabelled: Insufficient intake of water may influence the balance of water in the human body. In this study, we explore the impacts of water supplementation on body composition indices among young adults after 12 h of water restriction, with the aim to determine the optimum volume of water for improving body water composition. A randomized controlled trial study was conducted among 64 young men and women in Baoding, China.

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The purposes of this study were to explore the drinking patterns, and urinary and plasma hydration biomarkers of young adults with different levels of habitual total drinking fluid intake. A cross-sectional study was conducted among 111 young male athletes in Beijing, China. Total drinking fluids and water from food were assessed by a 7-day, 24-h fluid intake questionnaire and the duplicate portion method, respectively.

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Background: Few studies on measuring human energy expenditure with the doubly labeled water method has been conducted in China. The sources and loss of water among human body have never been systematically evaluated. Less data can be available for the development of the recommendation on energy expenditure and water intake.

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Article Synopsis
  • Trametes sanguinea Lloyd total polysaccharide (TsLTP) was extracted and characterized, revealing two key components, TsL1 and TsL2, with distinct sugar compositions and structures.
  • TsL1 includes various linked sugars like mannose and glucose in specific molar ratios, while TsL2 mainly consists of glucose with its own unique links.
  • Notably, TsLTP showed strong inhibitory effects on blood vessel growth in certain cellular models, suggesting potential applications in tumor therapy.
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The body's water and sodium balances are tightly regulated and monitored by the brain. Few studies have explored the relationship between water and salt intake, and whether sodium intake with different levels of fluid intake leads to changes in hydration status remains unknown. The aim of the present study was to determine the patterns of water intake and hydration status among young adults with different levels of daily salt intakes.

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Water is an essential nutrient for humans. A cross-sectional study was conducted among 159 young adults aged 18-23 years in Hebei, China. The total drinking fluids and water from food were obtained by 7-day 24 h fluid intake questionnaires and the duplicate portion method, respectively.

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The brain is approximately 75% water. Therefore, insufficient water intake may affect the cognitive performance of humans. The present study aimed to investigate the effects of water restriction and supplementation on cognitive performances and mood, and the optimum amount of water to alleviate the detrimental effects of dehydration, among young adults.

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Background: Psoriasis is a common chronic inflammatory skin disorder that causes patches of thick red skin and silvery scales and affects 1-3% of the population, which reduces patient's quality of life. Understanding the pathogenesis of psoriasis is crucial for developing novel therapeutic strategies.

Methods: HaCaT and NHEK cells were treated with TNF-α in vitro.

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: Promotion of a healthy lifestyle is considered a good strategy for dealing with chronic diseases. Mobile-based lifestyle interventions have shown beneficial effects in the control and treatment of chronic diseases such as diabetes, obesity and metabolic syndrome. Current clinical trials for mobile-based lifestyle intervention were mainly conducted among non-elderly populations, thus well-designed trials performed among the elderly who are more susceptible to chronic diseases are needed.

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Aim: To investigate the urination behaviours of senior citizens in China.

Methods: Stratified random sampling was used to recruit senior citizens who met the inclusion criteria from five cities in China. After training by researchers, participants recorded their urination behaviours in real time by using the validated 7-day 24-hour urination behaviour record, which consisted of frequency of urination, time of urination, urinary urgency and urine colour.

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