[Comparison of open reduction hollow nail anchoring system with loop plate fixation under arthroscopy for the treatment of posterior cruciate ligament avulsion fractures].

Objective: To compare clinical effect between open reduction and fixation with cannulated screw and threaded rivet via posteromedial approach versus arthroscopic Endobutton plate fixation in treating posterior cruciate ligament avulsion fractures.

Methods: Clinical data of 38 patients with posterior cruciate ligament avulsion fractures from July 2020 to December 2021 were analyzed retrospectively, and divided into open reduction and internal fixation group (posterior medial approach hollow anchor system fixation) and arthroscopic fixation group (Endobutton with loop plate fixation under arthroscopy). There were 20 patients in open reduction and internal fixation group, including 16 males and 4 females, aged from 26 to 74 years old with an average of (42.

Progress on lysosomal PPT1-mediated regulation of cellular homeostasis and pathogenesis.

Palmitoyl protein thioesterase 1(PPT1) is a lysosomal enzyme that catalyzes the protein depalmitoylation. It is considered to play a crucial role in regulating lysosomes, mitochondria and lipid metabolism. PPT1 has been reported to play an important role in the occurrence and progression of diseases, such as neurological diseases and cancers.

Chromosome-level Dinobdella ferox genome provided a molecular model for its specific parasitism.

Background: Dinobdella ferox is the most frequently reported leech species parasitizing the mammalian nasal cavity. However, the molecular mechanism of this special parasitic behavior has remained largely unknown.

Methods: PacBio long-read sequencing, next-generation sequencing (NGS), and Hi-C sequencing were employed in this study to generate a novel genome of D.

The roles and mechanism of STIM1 in tumorigenesis and metastasis.

STIM1 (stromal interaction molecule 1) is one of the key components of the store operated Ca entry channel (SOCE), which is located on the endoplasmic reticulum membrane and highly expressed in most kinds of tumors. STIM1 promotes tumorigenesis and metastasis by modulating the formation of invadopodia, promoting angiogenesis, mediating inflammatory response, altering the cytoskeleton and cell dynamics. However, the roles and mechanism of STIM1 in different tumors have not been fully elucidated.

The role and regulatory mechanism of FSCN1 in breast tumorigenesis and progression.

FSCN1, an actin-bundling protein, is highly expressed in almost all metastatic tumors and is associated with the poor prognosis. In breast cancer FSCN1 is highly expressed in basal-like and triple negative subgroups. There is significant progress in understanding the role of fascin in breast cancer.

Progress on the role and mechanism of MT1-MMP in tumor metastasis.

The matrix metallopeptidase family (matrix metallopeptidase, MMPs) is a class of zinc-dependent endopeptidases that can degrade most extracellular matrices. MT1-MMP (membrane type 1 metalloprotease) is an important metallopeptidase, which is located on plasma membrane and highly expressed in most tumors. MT1-MMP promotes cancer metastasis through affecting the extracellular matrix remodeling, angiogenesis, lipid metabolism, and inflammation.

Early and late recurrences in lymph node-negative gastric cancer: a retrospective cohort study.

Background: Predictors of recurrence in patients with lymph node-negative gastric cancer (GC) who have undergone curative resection have been widely investigated, but not the effects of predictors on timing of recurrence.

Objective: Determine the factors associated with early and late recurrence in patients with node-negative GC.

Design: Retrospective cohort.

Lymph node ratio-based the ypTNrM staging system for gastric cancer after neoadjuvant therapy: a large population-based study.

Purposes: The lymph node ratio (LNR) has been considered a better prognostic factor than traditional N staging in patients with gastric cancer (GC), but its accuracy is unclear for those who receive neoadjuvant therapy (NAT). We aimed to compare the node ratio (Nr) staging with the ypN staging and to thereby develop a modified staging system incorporating Nr staging.

Methods: A total of 1791 patients who underwent gastrectomy after NAT in the Surveillance, Epidemiology, and End Results database were retrospectively analyzed.

[Distribution Characteristics of Viruses Microorganisms in a Water Supply System with Combined Ultraviolet Chloramine Disinfection].

To study the effect of combined ultraviolet (UV) chloramine disinfection on viruses in a drinking water supply system, a full-scale experiment was conducted to analyze the distribution, variability, community structure, and hosts of viruses using metagenomics. The results showed that the combined UV chloramine process reduced the number of virus species (6.13%) and gene abundance (51.

First Report of Leaf Blotch of Caused by in China.

Salix babylonica L. (weeping willow) is an important ornamental tree commonly planted in China. Since 2018, a new disease with a high incidence has been observed on S.

Prognostic value of lymphocyte-to-C-reactive protein ratio in patients with gastric cancer after surgery: a multicentre study.

Objective: The immune inflammation-based score is recognized as a prognostic marker for cancer. However, the most accurate prognostic marker for patients with gastric cancer remains undetermined. We aimed to evaluate the predictive value of the lymphocyte-to-C-reactive protein ratio for outcomes in gastric cancer patients after radical gastrectomy.

[Effect of Qingyi Chengqi Decoction on severe acute pancreatitis patients: a clinical study].

Objective: To observe the change of intra-abdominal pressure (IAP) in severe acute pancreatitis (SAP) patients, and to study the effect of Qingyi Chengqi Decoction (QCD) on it.

Methods: Eighty-six SAP patients from Department of General Surgery and Department of Digestive Diseases, Qingyang People's Hospital, Gansu Province, who were in line with diagnosis standard of SAP, were assigned to the treatment group (44 cases) and the control group (42 cases) from March 2012 to May 2013. All patients received routine Western medicine.

[Discussion on five methods used for the determination of temporal clustering on infectious diseases].

To demonstrate and evaluate five different methods in the determination of temporal clustering on infectious diseases. The incidence rates of bacillary dysentery in Jinshui district, Zhengzhou city, Henan province from 2008 to 2010 were analyzed by 5 different methods-Cluster Analysis, Runs Test, Negative Binomial Distribution, Circular Distribution and Concentration Ratio. Through Cluster Analysis, data showed that the epidemic period was from May to Sept.

[The spatial distribution and dynamics of human rabies cases at the county level in Henan province].

Objective: To study the spatial distribution and dynamics of human rabies cases at the county level, in Henan province to provide scientific evidence for the development of control program on rabies.

Methods: Data of human rabies cases at the county level from 2004 to 2010 in Henan province were analyzed by Poisson distribution and negative binomial distribution. Data calculation was conducted manually.

[A study on the bonding properties of four resin cements].

Objective: To evaluate the dentin and enamel bonding strength and resin-dentin interfaces of four resin cements.

Methods: Twenty-four sound freshly extracted molars were sectioned with low-speed saw under running water. Two mesial-distal enamel disc and two buccal-lingual dentin discs were sectioned from each molar.

[Effects of Swan-like Shape Memory Connector on stress shielding rate and callus development during experimental fracture healing process].

Objective: To investigate the stress shielding rate, ultrastructural and biomechanical property of the healing bone fixed by Swan-like Shape Memory Connector (SMC) during experimental fracture healing in rabbits.

Methods: Unilateral osteotomy of left humeral diaphysis was performed in 140 adult New Zealand rabbits. The humeral fracture was fixed with SMC in study group and 4-hole dynamic compression plate (DCP) in control group.

[Analyses on the isolation and characterization of canine rabies virus isolates in Henan].

Objective: To analyze the genetic characteristics of two rabies virus isolates from Henan province and to compare their relations hip with known rabies virus isolates and vaccine strains.

Methods: Rabies viral antigens were detected in 100 canine brains by immunofluorescence assay method. Rabies virus was isolated through inoculating the suspensions of positive brains into suckling mice.

[Genetics subtypes and distribution of Seoul virus in Henan].

Objective: To investigate the sub-genotypes and distribution ot Seoul virus in Henan.

Methods: Rodents were collected in the major epidemic areas and rats lungs were studied by indirect immunofluorescence assay. Partial M and S segments were amplified with nested reverse transcription-polymerase chain reaction using Hantavirus genotype-specific primers, sequenced, analyzed and compared with other known sequences.