Circumferential Reconstruction of Subaxial Cervical and Cervicothoracic Spine by Simultaneously Combined Anterior-posterior Approaches in the Sitting Position.

Objective: To introduce and analyze the feasibility of a new surgical strategy for circumferential reconstruction of subaxial cervical and cervicothoracic spine by simultaneously combined anterior-posterior approach in the sitting position.

Methods: A retrospective review was performed for seven patients who underwent the above surgical procedure between July 2011 and January 2015. Among the seven patients, there were six men and one woman, with an average age of 52 years (range, 36-79 years).

[Insertion technique and clinical application of regional method axis pedicle screw].

Objective: To explore the clinical efficacies and outcomes of regional method axis pedicle screw insertion technique.

Methods: During the period of April 2004 to June 2010, a total of 23 cases with traumatic instability of upper cervical vertebrae were recruited. There were 19 males and 4 females with a mean age of 45.

Methotrexate-mediated inhibition of RAD51 expression and homologous recombination in cancer cells.

Background: Methotrexate is an inhibitor of folic acid metabolism. Homologous recombination is one of the most important ways to repair double-stranded breaks in DNA and influence the radio- and chemosensitivity of tumor cells. But the relationship between methotrexate and homologous recombination repair has not been elucidated.

[Lateral position one-stage combined posteroanterior approaches for the treatment of lumbosacral tuberculous spondylitis].

Objective: To investigate the feasibility of a one-stage combined posteroanterior approaches for the treatment of lumbosacral tuberculous spondylitis with the patients lying in a lateral position.

Methods: A retrospective review was conducted for 15 patients with lumbosacral tuberculosis undergoing one-stage combined posteroanterior approaches for radical lesion resection and reconstruction. All patients were observed and evaluated by clinical and imaging studies.

Assessing validation of dual fluoroscopic image matching method for measurement of in vivo spine kinematics.

Background: Accurate knowledge of the spinal structural functions is critical to understand the biomechanical factors that affect spinal pathology. Many studies have investigated the human vertebral motion both in vitro and in vivo. However, determination of in vivo motion of the vertebrae under physiologic loading conditions remains a challenge in biomedical engineering because of the limitations of current technology and the complicated anatomy of the spine.

[Effect of intervertebral position on range of motion after artificial lumbar total disc replacement and clinical management].

Objective: To discuss the effect of SB Charité lumbar artificial disc position on intervertebral range of motion (ROM) and clinical management.

Methods: Between 2004 and 2007, 30 discogenic low back pain patients confirmed by discography underwent 1/2-level total disc replacement (TDR) implantation with 32 prostheses. There were 12 males and 18 females with a mean age of 44 years old (range: 28-55).

[Mini-invasive extraperitoneal approach for anterior lumbar surgery].

Objective: To study a mini-invasive extraperitoneal approach to lumbar spine and discuss its exposure technique, complications and management.

Method: Anterior lumbar surgery was performed in 52 patients via the mini-invasive anterior extraperitoneal approach. Diagnoses included lumbar degenerative instability (n=23), discogenic lumbar pain (n=25), lumbosacral congenital deformity (n=2) and revision after posterior laminectomy & discectomy (n=2).