Multimodality Therapy and Survival Outcomes in Resectable Primary Small Cell Carcinoma of the Esophagus: A Multicenter Retrospective Study.

Background: Currently, optimal treatment strategy for resectable primary small cell carcinoma of the esophagus (PSmCCE) remains controversial. To address this, we conducted a multicenter study to evaluate treatment patterns and long-term survival of PSmCCE patients who underwent radical resection.

Methods: This retrospective multicenter study included resected PSmCCE patients who received radical resection at seven high-volume cancer centers.

Pathologic responses and surgical outcomes after neoadjuvant immunochemotherapy versus neoadjuvant chemoradiotherapy in patients with locally advanced esophageal squamous cell carcinoma.

Background: Currently, the role of immunotherapy in neoadjuvant setting for patients with locally advanced esophageal squamous cell carcinoma (ESCC) is gradually attracting attention. Few studies compared the efficacy of neoadjuvant immunochemotherapy (NICT) and neoadjuvant chemoradiotherapy (NCRT). Our study aimed to compare treatment response and postoperative complications after NICT followed by surgery with that after conventional NCRT in patients with locally advanced ESCC.

Tc bone scintigraphy does not affect preoperative workup for patients with potentially resectable esophageal squamous cell carcinoma.

Background: Tc bone scintigraphy (BS) is the mainstay and most widely used technique in evaluation of bone metastasis (BM) in China. This study aimed to investigate the value of Tc BS in preoperative workup for patients with potentially resectable (cT N ) esophageal squamous cell carcinoma (ESCC).

Methods: This prospective cross-section clinical trial (ChiCTR1800020304) enrolled a total of 385 patients with ESCC diagnosed at thoracic surgery clinic from October 2018 to September 2020.

CircRNA CircZMYM4 inhibits the growth and metastasis of lung adenocarcinoma via the miR-587/ODAM pathway.

Circular RNAs (circRNAs) are known to regulate tumorigenesis. In this study, circRNAs microarray was used to analyze the circRNA expression in lung adenocarcinoma (LUAD) tissues, and CircRNA zinc finger MYM-type containing 4(circZMYM4) was selected for further analysis. In this study, we detected circZMYM4 expression in LUAD specimens and cell lines using RT-PCR.

Treatment and Prognosis of Resectable Cervical Esophageal Cancer: A Population-Based Study.

Background: The optimal treatment strategy for resectable cervical esophageal cancer remains controversial. This study aimed to explore prognostic factors and optimal treatment strategies in the context of staging.

Methods: In this population-based study, 1371 patients with resectable cervical esophageal cancer were identified in the Surveillance, Epidemiology, and End Results database.

Patient prognostic scores and association with survival improvement offered by postoperative radiotherapy for resected IIIA/N2 non-small cell lung cancer: A population-based study.

Background: Currently, there is no consensus on the role of postoperative adjuvant radiotherapy (PORT) for resected stage IIIA/N2 non-small cell lung cancer (NSCLC). Our study sought to determine which patients may be able to benefit from PORT, based on a patient prognostic score.

Methods: A retrospective cohort study was conducted to identify patients diagnosed with IIIA/N2 NSCLC between 1988 and 2016 in the SEER database.

[Effects of Chelate GLDA on the Remediation of Cadmium Contaminated Farmland by Schum].

In order to clarify the effects of chelate tetrasodium glutamate diacetate (GLDA) on the remediation of cadmium (Cd) contaminated farmland by Schum, GLDA was applied in different methods within 60 days:total application doses of 585, 1170, and 2340 kg·hm were equally divided into 1-4 applications, respectively, and the time intervals of 2-4 applications were 30, 20, and 15 days, respectively. The biomass, Cd content, and amount of Cd extracted from aboveground parts of Schum, in addition to the pH, dissolved organic carbon (DOC) mass concentration, and other indicators in soil were analyzed. The results showed that the biomass and Cd content of the aboveground parts of Schum increased significantly when GLDA was applied many times at a low application dose.

Comparison of neoadjuvant chemoradiotherapy and neoadjuvant chemotherapy for esophageal cancer: a meta-analysis.

To compare the clinical efficacy of neoadjuvant chemoradiotherapy (nCRT) and neoadjuvant chemotherapy (nCT) for esophageal cancer. Randomized controlled trials reporting on the comparison of nCRT and nCT for esophageal cancer were identified. Three eligible randomized controlled trials were identified and included with a total of 375 patients (189 nCRT, 186 nCT).

Application of bronchoscope for the placement of nasoenteric feeding tube in patients with esophagectomy: a novel technique.

Background: Currently the available techniques for the placement of nasoenteric feeding tube (NET), utilizing transnasal gastroscope are fast and tolerable, which is known as the most popular method. However, lots of hospitals don't have this endoscopic system. Bronchoscope, which is the basic respiratory endoscope, not only has the advantages of transnasal endoscopy, but also is popular in common hospitals.

Embedded Three-Layer Esophagogastric Anastomosis Reduces Morbidity and Improves Short-Term Outcomes After Esophagectomy for Cancer.

Background: There exists great controversy regarding the use of esophagogastric anastomotic techniques in the treatment of esophageal cancer. The aim of this study was to compare two types of cervical esophagogastric anastomoses with respect to the reduction of postoperative anastomotic leaks, stenosis, and gastroesophageal reflux.

Methods: From June 2010 to September 2013, 339 patients who underwent two different cervical esophagogastric anastomotic procedures after thoracolaparoscopic esophagectomy for esophageal cancer were identified.

Thyroid function is associated with non-alcoholic fatty liver disease in chronic hepatitis B-infected subjects.

Background And Aims: Associations between thyroid function and non-alcoholic fatty liver disease (NAFLD) are unknown in chronic hepatitis B (CHB)-infected patients. Thus, the aim of the study was to investigate the prevalence of thyroid dysfunction and its relationship with NAFLD in CHB.

Methods: Consecutive naive CHB infected patients that had undergone liver biopsy and serum thyroid function tests between January 2007 and December 2011 were retrospective analyzed.

Serum carcinoembryonic antigen levels before initial treatment are associated with EGFR mutations and EML4- ALK fusion gene in lung adenocarcinoma patients.

Background: Epidermal growth factor receptor (EGFR) mutations and echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) define specific molecular subsets of lung adenocarcinomas with distinct clinical features. Our purpose was to analyze clinical features and prognostic value of EGFR gene mutations and the EML4-ALK fusion gene in lung adenocarcinoma.

Patients And Methods: EGFR gene mutations and the EML4-ALK fusion gene were detected in 92 lung adenocarcinoma patients in China.

Early oral feeding following thoracolaparoscopic oesophagectomy for oesophageal cancer.

Objectives: Nil-by-mouth with enteral tube feeding is widely practised for several days after resection and reconstruction of oesophageal cancer. This study investigates early changes in postoperative gastric emptying and the feasibility of early oral feeding after thoracolaparoscopic oesophagectomy for patients with oesophageal cancer.

Methods: Between January 2013 and August 2013, gastric emptying of liquid food and the feasibility of early oral feeding after thoracolaparoscopic oesophagectomy was investigated in 68 patients.

[Comparison of thoraco-laparoscopic and open three-field subtotal esophagectomy for esophageal cancer].

Objective: To evaluate the safety and efficacy of thoraco-laparoscopic subtotal esophagectomy in the treatment of esophageal cancer.

Methods: Clinical data of 98 patients with esophageal cancer who underwent thoraco-laparoscopic subtotal esophagectomy from March 2009 to October 2011 were retrospectively analyzed. One hundred and five patients were served as controls who underwent open three-field subtotal esophagectomy in the same period.

Preliminary study of osmotic membrane bioreactor: effects of draw solution on water flux and air scouring on fouling.

Preliminary study on a novel osmotic membrane bioreactor (OMBR) was explored. Objective of this study was to investigate the effects of draw solution on membrane flux and air scouring at the feed side on fouling tendency in a pilot OMBR system composing the anoxic/aerobic and forward osmosis (FO) processes. Domestic sewage was the raw feed, FO membrane from HTI and NaCl/MgSO4 draw solutions were used in the experiments.

Experimental studies and modeling on concentration polarization in forward osmosis.

Concentration polarization (CP) is an important issue in forward osmosis (FO) processes and it is believed that the coupled effect of dilutive internal CP (DICP) and concentrative external CP (CECP) limits FO flux. The objective of this study was to distinguish individual contribution of different types of DICP and CECP via modeling and to validate it by pilot studies. The influence of DICP/CECP on FO flux has been investigated in this study.

Pilot study of a submerged membrane bioreactor for water reclamation.

The objective of this pilot study was to investigate the operational conditions of newly developed MBR modules for water reclamation under tropical conditions. MUDC-620A MBR modules with hollow fibre PVDF membranes from Asahi-Kasei Chemicals were used in the study. The pilot plant with capacity of 50 m(3)/d was operated continuously (24-hour) over four months on site of Ulu Pandan Water Reclamation Plant (UPWRP) in Singapore.

A dual membrane UF/RO process for reclamation of spent rinses from a nickel-plating operation--a case study.

The objective of this work was to conduct treatability studies on rinse wastewater from process lines of a typical nickel-plating plant for reuse. The study comprised of three steps: (1) a plant process review and the treatability of different combinations of simulated spent rinses in the laboratory; (2) a variability monitoring of a combined rinse at the plant and a treatability study on a combined rinse in the laboratory; (3) a pilot study for reclamation of the combined rinse on site. The study established an optimum dual membrane ultrafiltration (UF)/reverse osmosis (RO) process for treating a combined liquor of spent alkaline, acidic and nickel-plating rinses which resulted in a treated water of a quality suitable for reuse as substitute for town water for the purpose of rinsing.