Genetic source tracking of an anthrax outbreak in Shaanxi province, China.

Background: Anthrax is an acute zoonotic infectious disease caused by the bacterium known as Bacillus anthracis. From 26 July to 8 August 2015, an outbreak with 20 suspected cutaneous anthrax cases was reported in Ganquan County, Shaanxi province in China. The genetic source tracking analysis of the anthrax outbreak was performed by molecular epidemiological methods in this study.

[Research progress on tranexamic acid application strategy in total knee arthroplasty].

Tranexamic acid(TXA) as an antifibrinolytic drugs used to reduce the total knee arthroplasty(TKA) postoperative blood loss is a hot issue in recent years. Such as blood loss, hemoglobin, transfusion rate and other relevant indexs effected by the impact of total knee replacement have been studied and investigated by many scholars. There is no a gold standard about how to safely and effectively apply the TXA.

Analysis of association among clinical features and shorter leukocyte telomere length in mitochondrial diabetes with m.3243A>G mitochondrial DNA mutation.

Background: Mitochondrial diabetes is a kind of rare diabetes caused by monogenic mutation in mitochondria. The study aimed to summarize the clinical phenotype profiles in mitochondrial diabetes with m.3243 A>G mitochondrial DNA mutation and to investigate the mechanism in this kind of diabetes by analyzing the relationship among clinical phenotypes and peripheral leukocyte DNA telomere length.

Barker-coded excitation in ophthalmological ultrasound imaging.

High-frequency ultrasound is an attractive means to obtain fine-resolution images of biological tissues for ophthalmologic imaging. To solve the tradeoff between axial resolution and detection depth, existing in the conventional single-pulse excitation, this study develops a new method which uses 13-bit Barker-coded excitation and a mismatched filter for high-frequency ophthalmologic imaging. A novel imaging platform has been designed after trying out various encoding methods.

Quercetin: a potential natural drug for adjuvant treatment of rheumatoid arthritis.

Rheumatoid arthritis (RA) is the rheumatism mainly manifested as disabling joint disease and mainly involves hands, wrists, feet and other small joints. Recurrent arthritis attacks, synovial cell hypertrophy and hyperplasia and bone and cartilage damages eventually lead to joint dysfunction and other complications, and there is no cure. Quercetin (QU) is a kind of natural flavonoids, with lipid-lowering, anti-inflammatory and other pharmacological activities, and minor toxic side effects.

[Development of a transmitting and echo receiving system for high frequency ultrasonic imaging].

A transmitting and receiving system used in high frequency ultrasound imaging is introduced and has been used for image collection of 10MHz, 20MHz and 50MHz HF ultrasonic imaging equipment. Its experimental results show that this transmitting and receiving system is capable of obtaining a better quality of medical images.

[Role of intestinal lymphatic pathway in pathogenesis of intestine-derived bacteria/endotoxin translocation in rats in shock].

Objective: To observe the changes of toxic substances in mesenteric lymph and portal vein blood of rats in hemorrhagic shock, and the influence of mesenteric lymph duct ligation on level of endotoxin (ET) in organs and bacterial contents in mesenteric lymph nodes (MLN) and spleen in rats with hemorrhagic shock, and to evaluate the role of lymphatic pathway in pathogenesis of intestine-derived bacteria/endotoxin translocation (BET) in rats with shock.

Methods: Twenty-four male Wistar rats were randomly divided into the shock group and control group. A model of serious hemorrhagic shock was reproduced by blood shedding to maintain the blood pressure at 40 mm Hg (1 mm Hg=0.

[Clinical experience of treatment of 275 mandible fractures].

Objective: To evaluate the treatment effect of mandible fractures.

Methods: Clinical data of 275 mandibular fracture patients of Tongchuan people's hospital were analysed.

Results: (1) The systemic health of 27 non-surgery cases were influenced during the intermaxillary ligation and 3 cases of them had deformity of maxillofacial region.

[Correlation between point mutation frequency of MBL gene exon I and plasma MBL concentration in healthy Mongolians].

Aim: To investigate the point mutation at codon 54 of mannose binding lectin (MBL) gene, detect the plasma MBL level, and analyze the correlation between the gene mutation frequency and plasma MBL concentration.

Methods: A method for detecting MBL gene point mutation (PCR-RFLP) was established with self-designed primers according to MBL genomic sequence. The plasma MBL concentration was detected by MBL Oliger ELISA kit.