Publications by authors named "Jian-hua LI"

Reclamation is essential for restoring the ecological function of soil in mining areas. However, the microbiological mechanism of soil ecological function reconstruction under different reclamation measures still needs to be clarified. Clarifying the characteristics of soil bacterial and fungal communities, assembly mechanisms, and their relationship with physicochemical properties under different reclamation measures is crucial for reshaping the ecological stability of soil in mining areas.

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  • Heart failure (HF) is linked to brain abnormalities and cognitive impairments, with this study analyzing structural and functional brain changes in 49 chronic HF patients compared to 49 healthy controls.
  • Structural MRI revealed reduced gray matter volume (GMV), impaired white matter integrity, and decreased functional connectivity in HF patients, with significant correlations between GMV and cognitive performance.
  • The findings suggest that GMV could be a useful neuroimaging biomarker for cognitive issues and a potential target for future neuroprotective therapies in chronic HF patients.
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  • A multicenter randomized controlled trial in China investigated the impact of adding coronary CT-derived fractional flow reserve (CT-FFR) to routine coronary CT angiography (CCTA) on the need for invasive coronary angiography (ICA) and major adverse cardiovascular events (MACE) in patients with suspected coronary artery disease (CAD).
  • The study involved 5,297 participants, showing that the CCTA plus CT-FFR group had a lower ICA rate (10.0%) compared to the CCTA alone group (12.4%) over a 90-day follow-up.
  • While MACE rates were similar between groups, the CCTA plus CT-FFR approach resulted in fewer cardiac events after one year (0.5%
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Background: Liver transplantations (LTs) with extended criteria have produced surgical results comparable to those obtained with traditional standards. However, it is not sufficient to predict hepatocellular carcinoma (HCC) recurrence after LT according to morphological criteria alone. The present study aimed to construct a nomogram for predicting HCC recurrence after LT using extended selection criteria.

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Background: Hypertension, a prevalent disease, is a significant risk factor for coronary heart disease. Huoxue Qianyang Qutan Recipe (HQQR), a traditional Chinese herbal remedy, has been used for treating hypertension over several years.

Objective: This study assesses HQQR's efficacy for controlling blood pressure among patients with hypertension related to blood stasis, yang hyperactivity and phlegm.

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How plants find a way to thrive in alpine habitats remains largely unknown. Here we present a chromosome-level genome assembly for an alpine medicinal herb, (Caprifoliaceae), and 13 transcriptomes from other species of Dipsacales. We detected a whole-genome duplication event in that occurred prior to the diversification of Dipsacales.

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A mounting body of evidences suggests that patients with chronic heart failure (HF) frequently experience cognitive impairments, but the neuroanatomical mechanism underlying these impairments remains elusive. In this retrospective study, 49 chronic HF patients and 49 healthy controls (HCs) underwent brain structural MRI scans and cognitive assessments. Cortical morphology index (cortical thickness, complexity, sulcal depth and gyrification) were evaluated.

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The tribe Collabieae (Epidendroideae, Orchidaceae) comprises approximately 500 species. Generic delimitation within Collabieae are confusing and phylogenetic interrelationships within the Collabieae have not been well resolved. Plastid genomes and nuclear internal transcribed spacer (ITS) sequences were used to estimate the phylogenetic relationships, ancestral ranges, and diversification rates of Collabieae.

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Background: Normal bile is sterile. Studies have shown that cholangitis after liver transplantation (LT) was associated with a relatively poor prognosis. It remains unclear whether the bacteriobilia or fungibilia impact the patient outcomes in LT recipients, especially with donation after circulatory death (DCD) allografts, which was correlated with a higher risk of allograft failure.

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  • Placental ischemia from poor remodeling of uterine spiral arteries is linked to preeclampsia development.
  • The study investigates how endothelial progenitor cells, which help repair blood vessels, are affected during this remodeling process, particularly in women with preeclampsia.
  • Findings indicate that dysfunctional endothelial progenitor cells lead to artery narrowing and decreased blood flow to the placenta, providing insights into the causes of preeclampsia.
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Background: While the impact of depression on cognition is well-documented, the relationship between feelings and cognition has received limited attention.

Aim: To explore the potential association between feelings and cognition with a two-sample Mendelian randomization (MR) analysis.

Methods: Our analysis utilized genome-wide association data on various feelings (fed-up feelings, = 453071; worrier/anxious feelings, = 450765; guilty feelings, = 450704; nervous feelings, = 450700; sensitivity/hurt feelings, = 449419; miserableness, = 454982; loneliness/isolation, = 455364; happiness, = 152348) in the European population and their impact on cognitive functions (intelligence, = 269867).

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Background: This study aimed to investigate the efficacy of circuits-based paired associative stimulation (PAS) in adults with amnestic mild cognitive impairment (aMCI).

Methods: We conducted a parallel-group, randomised, controlled clinical trial. Initially, a cohort of healthy subjects was recruited to establish the cortical-hippocampal circuits by tracking white matter fibre connections using diffusion tensor imaging.

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Purpose: To identify long-term predictors of distant metastases (DM) and the overall survival (OS) of follicular thyroid cancer (FTC) patients who underwent radioactive iodine (RAI) therapy. And to expand the knowledge about the clinical course and experience of RAI treatment for FTC.

Materials: A total of 117 FTC patients who underwent RAI therapy at our institution from 2005 to 2020 were retrospectively studied.

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  • Choline acetyltransferase (ChAT) helps make a chemical called acetylcholine that can reduce inflammation in the body, especially through the vagus nerve.
  • Scientists tested if ChAT in the blood changes during inflammation and if it can help control the release of chemicals that cause inflammation.
  • They found that ChAT levels in mice increased after inflammation and that giving ChAT could lower inflammation, suggesting it might be useful as a treatment for inflammatory diseases in humans.
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Objective: To summarize and discuss the guiding role of endoscopic ultrasound (EUS) in selecting endoscopic treatments for submucosal tumors (SMTs) in the upper gastrointestinal tract.

Methods: A retrospective investigation was conducted on 156 SMT patients who received endoscopic resection guided by EUS in the endoscopy center of the Second Affiliated Hospital of Guangzhou University of Chinese Medicine from May 2019 to September 2021. Next, the size, pathological type, and distribution of lesions were analyzed; the correlation of the tumor origin with distribution of lesions and selection of treatments was explored; and the consistency of preoperative EUS diagnosis and postoperative pathological diagnosis was summarized and analyzed.

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Objective: To explore the benefits and risks of early enteral nutrition (EN) in patients receiving extracorporeal membrane oxygenation (ECMO).

Methods: A single center retrospective review was performed including patients receiving ECMO for more than 24 h from May 2014 to July 2021.

Results: A total of sixty-five patients were enrolled, of which thirty-six patients (55.

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Background: Thousands of healthy babies are born from in vitro maturation (IVM) procedures, but the rate of efficiency differs with the source of immature oocytes obtained. Recently, there are different IVM protocols proposed for infertility treatment and fertility preservation.

Methods: Based on the literature, the clinical application for IVM of immature oocytes was summarized.

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Background: Inflammation, the physiological response to infection and injury, is coordinated by the immune and nervous systems. Interleukin-1β (IL-1β) and other cytokines produced during inflammatory responses activate sensory neurons (nociceptors) to mediate the onset of pain, sickness behavior, and metabolic responses. Although nociceptors expressing Transient Receptor Potential Ankyrin-1 (TRPA1) can initiate inflammation, comparatively little is known about the role of TRPA1 nociceptors in the physiological responses to specific cytokines.

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Tacrolimus, a calcineurin inhibitor widely used as a potent immunosuppressant to prevent graft rejection, exhibits nonlinear kinetics in patients with kidney transplantation and nephrotic syndrome. However, whether nonlinear drug metabolism occurs in adult patients undergoing liver transplantation remains unclear, as do the main underlying mechanisms. Therefore, here we aimed to further confirm the characteristics of nonlinearity through a large sample size, and determine the potential influence of nonlinearity and its possible mechanisms.

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Purpose: The oral microbiota is closely associated with systemic health, but few studies have investigated the oral microbiota in patients with obstructive sleep apnea (OSA). This study aimed to identify the variation of oral microbiota among patients with severe OSA, and the change of oral microbiota after treatment with continuous positive airway pressure (CPAP).

Methods: Participants were enrolled in the study from November 2020 to August 2021.

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To investigate the association between obstructive sleep apnea (OSA) severity and baseline serum cystatin C (Cys-C) concentration and to explore the association between baseline serum Cys-C and long-term cardiovascular outcomes and mortality in older patients with OSA. Between January 2015 and October 2017, a total of 1107 consecutive eligible older patients (≥60 years) with OSA were included in this multicenter, prospective cohort study, and baseline demographics, clinical characteristics, sleep parameters, and follow-up outcomes were collected. Participants were divided into different groups based on baseline serum Cys-C levels.

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Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and has a high recurrence rate. Accurate prediction of recurrence risk is urgently required for tailoring personalized treatment programs for individual HCC patients in advance. In this study, we analyzed a gene expression dataset from an HCC cohort with 247 samples and identified five genes including , , , , and as the variables for the prediction of HCC recurrence, especially the early recurrence.

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Objective: It is commonly believed that the oocytes from small follicles are unhealthy when a dominant follicle (DF) is recruited in the ovaries, especially when the DF is ovulated. This study aims to confirm whether the presence or ovulation of DF at the time of retrieval affects the clinical outcome of the natural cycle IVF with maturation (NC-IVF/M) treatment.

Methods: Data were collected from 446 women with regular menstrual cycle and 536 retrieval cycles using NC-IVF/M treatment.

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