Native Defect-Dependent Ultrafast Carrier Dynamics in p-Type Dopable Wide-Bandgap NiO.

NiO is a wide-bandgap p-type metal oxide that has extensive applications in optoelectronics and photocatalysts. Understanding the carrier dynamics in p-type NiO is pivotal for optimizing device performance, yet they remain largely unexplored. In this study, we employed femtosecond transient absorption spectroscopy to delve into the dynamics of photogenerated carriers in NiO films containing distinct prominent native defects: undoped NiO with oxygen vacancies () and O-rich NiO (denoted as NiO) with nickel vacancies ().

An injectable, biodegradable calcium phosphate cement containing poly lactic-co-glycolic acid as a bone substitute in ex vivo human vertebral compression fracture and rabbit bone defect models.

Unlabelled: Purpose/Aim of the study: To evaluate the biomechanical characteristics and biocompatibility of an injectable, biodegradable calcium phosphate cement (CPC) containing poly lactic-co-glycolic acid (PLGA).

Materials And Methods: A vertebral compression fracture model was established using 20 human cadaveric vertebrae (T11-L3) divided into CPC/PLGA composite versus PMMA groups for biomechanical testing. In addition, 35 New Zealand rabbits were used to evaluate biodegradability and osteoconductive properties of CPC/PLGA using a bone defect model.

[Antitumor effect of calcium phosphate cement incorporating doxorubicin microspheres].

Objective: To investigate the antitumor effect of calcium phosphate cement incorporated with doxorubicin microspheres.

Methods: The absorbance at 490 nm of SaoS-2 cells cultured for 5 days in the media containing the extract of the cement incorporating doxorubicin microspheres was measured using Cell Counting Kit-8. SaoS-2 cells were adjusted to the density of 2x10(7) ml(-1) and injected into the left buttock of nude mouse in the volume of 0.

[Histological changes of an injectable rhBMP-2/calcium phosphate cement in vertebroplasty of rhesus monkey].

Objective: The histological changes of rhBMP-2/calcium phosphate cement (CPC) were evaluated in vertebroplasty on nonhuman primate models in order to determine the feasibility of this carrier formulation instead of PMMA.

Methods: Percutaneous vertebroplasty (PVP) was performed in 4 adult rhesus monkeys which were evenly distributed in two groups. Ten vertebral bodies(VBs) from T10 to L7, of each rhesus were selected, and the 20 VBs in each group were randomly divided into 3 sub-groups.