Publications by authors named "Jian-Zhu Xie"
High expression of TGR5 predicts a poor prognosis in patients with pancreatic cancer.
Int J Clin Exp Pathol
July 2018
Article Synopsis
- Previous studies indicate that bile acids are linked to cancer progression, with the G-protein coupled bile acid receptor-1 (TGR5) being a notable connection.
- In this research, TGR5 expression was found to be significantly higher in pancreatic cancer tissues compared to normal tissues, correlating with lymph node metastasis and advanced tumor stage.
- The analysis revealed that high TGR5 expression is associated with decreased overall survival in pancreatic cancer patients, suggesting it may be an important prognostic marker.