Publications by authors named "Jian-Yun Gao"

Article Synopsis
  • Rice, a staple food, can enhance its nutritional value through fermentation with certain medicinal fungi.
  • Four fungi—Ganoderma boninense, Phylloporia pulla, Sanghuangporus sanghuang, and Sanghuangporus weigelae—were selected for further analysis after screening, revealing significant changes in their metabolic profiles.
  • Sanghuangporus weigelae resulted in rice with the highest nutritional and bioactive values, highlighting the potential of using medicinal fungi for improved functional food development.
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Extreme weather/climate events increased significantly because of global warming. Based on daily records from 16 meteorological stations in the Poyang Lake Basin (PLB) from 1959 to 2019, we comprehensively investigated the temporal-spatial and non-stationarity characteristics of extreme precipitation from three dimensions (intensity, frequency and duration) using PreWhite-ning Mann-Kendall (PWMK), extreme-point symmetric mode decomposition method (ESMD) and the generalized additive models for location, scale and shape (GAMLSS). The results showed that the intensity and frequency of extreme precipitation increased significantly in the PLB, while the duration of extreme precipitation decreased from 1959 to 2019.

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Objective: To observe the effects of moxibustion at different temperatures (38 ℃ and 45 ℃) on blood lipoids and serum level of oxidized low density lipoprotein (ox-LDL) and nitric oxide (NO) in rats with hyperlipidemia, and to explore the correlation between regulating blood fat and anti-oxidative stress and protection of vascular endothelium of moxibustion at 45 ℃.

Methods: According to random number table, 60 SD rats were randomly divided into a normal group, a model group, a moxibustion at 38 ℃ group and a moxibustion at 45 ℃ group, 15 rats in each group. The rats in the normal group received no treatment; the rats in the remaining three groups were fed with high-fat diet for 8 weeks to prepare rat models of hyperlipidemia.

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Background: The glacial-interglacial cycles in the Pleistocene caused repeated range expansion and contraction of species in several regions in the world. However, it remains uncertain whether such climate oscillations had similar impact on East Asian biota, despite its widely recognized importance in global biodiversity. Here we use both molecular and ecological niche profiles on 11 East Asian avian species with various elevational ranges to reveal their response to the late Pleistocene climate changes.

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Article Synopsis
  • The study investigates how miR-214 affects the development of hepatocellular carcinoma (HCC) by inhibiting the β-catenin signaling pathway.
  • Researchers created two cell lines: one expressing miR-214 and one as a control, comparing their growth, proliferation, and cell cycle characteristics.
  • Results showed that miR-214 significantly reduced cell growth and increased the proportion of cells in the G0/G1 phase while lowering β-catenin protein and its targets, demonstrating its potential as a therapeutic agent against HCC.
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Objective: To explore the effects and mechanism of electroacupuncture combined with medium frequency therapy on lumbar nerve root compression.

Methods: Seventy-two Sprague-Dawley (SD) rats were randomly divided into a normal group, a sham operation group, a model group, an electroacupuncture group (EA group), a medium frequency group(MF group) and an electroacupuncture combined with medium frequency group (EA + MF group), twelve rats in each group. Models were established by surgery except the normal group and the sham operation group.

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Article Synopsis
  • The article reviews the past 50 years of studies on acupoints and introduces the mechanism and technology behind resistance testing, highlighting its limitations.
  • * It presents a new method for determining signal transmission along meridians by combining electrical network theories with practical experiments.
  • * The findings indicate that signals from specific acupoint interactions and those along non-meridian paths differ significantly, supporting the use of electrical theories to analyze signal transmission in the body.
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Objective: To analyze the predominant genotypes of outer membrane porin I (PI) and to determine the correlation between G120 as well as A121 mutations in PI proteins and drug resistance in Neisseria gonorrhoeae isolates in the local area.

Methods: A double PCR to simultaneously detect both pIA and pIB genes, was established in this study. The target amplification products were T-A cloned and then sequenced to determine the mutations at G120, A121 and the specificity of double PCR.

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