Publications by authors named "Jian-Yuan Lin"

Background: Internal hernia is a rare cause of acute abdomen and intestinal obstruction in adults. Internal abdominal hernias include paraduodenal, perigastric, foramen of Winslow, intersigmoid, and post-anastomotic hernias and can be congenital or acquired. Internal hernias occur in 1%-2% of patients, and transmesocolic hernias are extremely rare.

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Article Synopsis
  • The study investigates how the Ampkα/Sirt1 pathway influences the severity of acute pancreatitis and related lung injury by reducing inflammation and cell death in pancreatic acinar cells.
  • Researchers utilized rat models and cell lines to demonstrate that activating Ampkα or overexpressing Spef2 lowers markers of oxidative stress, inflammation, and injury in acute pancreatitis.
  • The findings highlight a regulatory relationship between Spef2, Ampkα, and Sirt1, suggesting potential therapeutic targets for mitigating the effects of acute pancreatitis and associated complications.
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