[Accumulation of Sulfonamides and Macrolides Antibiotic Resistance Genes in Soils with Different Utilization Patterns in China].

To explore the variation in the absolute abundance of antibiotic resistance genes (ARGs) in different regions of China under different land use modes and different planting years, the qualitative and quantitative study of sulfonamide () and macrolide () ARGs and an integron gene () were conducted using ordinary PCR and the fluorescence quantitative technique. The results revealed that the frequencies of sulfonamides () and were all 100% in different soils, and the detection frequencies of macrolides () were 100% in facilities vegetable fields; however, in open vegetable fields, and open grain fields, the frequencies of were 94%, and those of were 92% and 90%, respectively. The absolute abundance of sulfonamide and macrolide ARGs was the highest in 15 years facilities vegetable soil in Heilongjiang Province.