The complete chloroplast genome of , a tree native to China with diverse beneficial medicinal applications.

In the present study, we announce the first complete chloroplast genome sequence of , a tree native to China with diverse beneficial uses. This complete chloroplast genome is 160,987 bp in length. In total, 130 genes were identified, including 85 protein-coding genes, 37 tRNA genes, and 8 rRNA genes.

Fecal microbiota transplantation confers beneficial metabolic effects of diet and exercise on diet-induced obese mice.

Diet and exercise are conventional methods for controlling body weight and are linked to alterations in gut microbiota. However, the associations of diet, exercise, and gut microbiota in the control of obesity remain largely unknown. In the present study, using 16S rRNA amplicon sequencing and fecal microbiota transplantation (FMT), normal fat diet (NFD), exercise and their combination resulted in improved metabolic profiles in comparison to sedentary lifestyle with high fat diet (HFD).

Therapeutic potential of microRNA let-7: tumor suppression or impeding normal stemness.

The first microRNA, let-7, and its family were discovered in Caenorhabditis elegans and are functionally conserved from worms to humans in the regulation of embryonic development and stemness. The let-7 family has been shown to have an essential role in stem cell differentiation and tumor-suppressive activity. Deregulating expression of let-7 is commonly reported in many human cancers.