Follow-up study of gallbladder stones in 44 children.

Background: Cholesterol stones affect a certain subpopulation of children. Concerns have been raised on the impact of gallbladder surgery on the growth of children and adolescents.

Aim: To study the population characteristics, clinical features, treatment, and prognosis of gallstones in children.

Gender difference in the neuroprotective effect of rat bone marrow mesenchymal cells against hypoxia-induced apoptosis of retinal ganglion cells.

Bone marrow mesenchymal stem cells can reduce retinal ganglion cell death and effectively prevent vision loss. Previously, we found that during differentiation, female rhesus monkey bone marrow mesenchymal stem cells acquire a higher neurogenic potential compared with male rhesus monkey bone marrow mesenchymal stem cells. This suggests that female bone marrow mesenchymal stem cells have a stronger neuroprotective effect than male bone marrow mesenchymal stem cells.

3-D spheroid culture of bone marrow mesenchymal stem cell of rhesus monkey with improved multi-differentiation potential to epithelial progenitors and neuron in vitro.

Background: Bone mesenchymal stem cells are an attractive source of cells with potential applications in ocular regenerative medicine. However, the low differentiation efficiency in the traditional two-dimensional (2-D) culture system limits their application for clinical therapy. Here, we describe a simple and innovative 3-D culture environment and assess the potential for bone mesenchymal stem cells to differentiate into a variety of cell types in the 3-D system.

Sexual dimorphism on the neurogenic potential of rhesus monkeys mesenchymal stem cells.

Bone marrow mesenchymal stem cells (BMSCs) have been shown to differentiate into cells of a neural lineage. However, no studies have examined whether gender influences the differentiation potential of BMSCs. Here, we explore the possible differences in BMSC's neurogenic potential in vitro between female rhesus monkey BMSCs (F-rhBMSCs) and male rhBMSCs (M-rhBMSCs).