Publications by authors named "Jian-Xian Tang"
Article Synopsis
- Six new triterpenoids (euphokanols A-F) and two new C-steroidal glycosides (euphokanosides A and B) were isolated from the roots of Euphorbia kansui, alongside fifty-four known compounds.
- The structures of the new compounds were established using advanced techniques such as NMR spectroscopy and mass spectrometry, with euphokanol A's configuration determined by electronic circular dichroism analysis.
- Several isolated compounds exhibited notable biological activities; for instance, some showed significant inhibition of nitric oxide production, while others demonstrated cytotoxic effects against specific cancer cell lines, particularly euphol, which selectively targeted human glioma stem cells.
Eight new iridoids, jatavaleridoids A-H (1-8), were isolated from the roots and rhizomes of Valeriana jatamansi. Their structures and absolute configurations were elucidated based on NMR and HRESIMS spectroscopic data, as well as quantum chemical calculation. Structurally, compounds 1-5 and 8 were rare iridoids with long-chain fatty acid esters at C-10.
View Article and Find Full Text PDFEleven new seco-iridoids, valeridoids G-Q (1-6 and 8-12), along with four known products, 9-epi-valtral C (7), desacylbaldrinal (13), 11-methoxyviburtinal (14) and baldrinal (15), were obtained from Valeriana jatamansi. Among them, the new compounds were identified by their NMR, HR-ESI-MS spectroscopic data and ECD calculation. Moreover, valeridoid N and O were a pair of C epimers, whose ether bonds between C-1 and C-3 opened, and new ether bonds formed between C-3 and C-6.
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