Publications by authors named "Jian-Rui Lv"
Background And Aim: Remimazolam tosilate (RT) is a new short-acting GABA(A) receptor agonist, having potential to be an effective option for procedural sedation. Here, we aimed to compare the efficacy and safety of RT with propofol in patients undergoing upper gastrointestinal endoscopy.
Methods: This positive-controlled, non-inferiority, phase III trial recruited patients at 17 centers, between September 2017 and November 2017.
Article Synopsis
- * Overall analysis found no significant association between rs4919510 and cancer risk across all genetic models but noted a reduced risk for colorectal cancer and a potential increased risk for papillary thyroid cancer based on specific genetic models.
- * The rs4919510 GG genotype was linked to poorer recurrence-free survival among cancer patients, indicating the need for further research on larger populations to confirm these findings.
Background/aims: Ghrelin can act as a signal for mealtime hunger and meal initiation. Amygdala is indispensable in appetitive behavior motivated by learned emotions. This study was to investigate the alteration of ghrelin in the amygdala of rats with chronic renal failure (CRF) and its relation with uremic anorexia.
View Article and Find Full Text PDFObjective: To investigate the effect of Bcl-2 overexpression on Fas and TNFR1-mediated apoptosis and its possible mechanism in rat hippocampus following global ischemia/reperfusion (IR).
Methods: Ninety healthy male SD rats were randomly divided into sham operated group, IR group and Bcl-2 overexpression group (BT group). Rat model of global IR was established by the 4-V0 method.
Objective: To investigate the protein levels of phospho-ERK and phospho-APE/Ref-1 in hippocampal neurons after global cerebral ischemia reperfusion in rats, and observe the relationship between transmembrane signal transduction and repair of DNA damage. The role of ERK signal transduction pathway following global cerebral ischemia reperfusion in rats is further discussed.
Methods: Ninety healthy male SD rats were divided into 3 groups randomly: Sham group (S group), Ischemia reperfusion group (IR group) and Pd98059 pretreatment/ischemia reperfusion group (PD group).