Publications by authors named "Jian-Ru Dong"
Front Aging Neurosci
May 2022
Article Synopsis
- Alzheimer's disease (AD) research has advanced, but the exact mechanisms and effective treatments remain unclear, with ApoA-I potentially influencing AD development by interacting with amyloid β (Aβ).
- A meta-analysis of 18 studies involving over 1,000 AD patients and healthy controls (HCs) found significantly lower ApoA-I levels in serum and plasma of AD patients compared to HCs, suggesting a potential link between ApoA-I deficiency and AD.
- Although CSF ApoA-I levels showed a non-significant increase in AD patients, the findings highlight ApoA-I's potential as a biomarker for AD diagnosis and its role in understanding the disease.
