CoQ10 alleviate preeclampsia symptoms by enhancing the function of mitochondria in the placenta of pregnant rats with preeclampsia.

: To assess whether supplementation with Coenzyme Q10 (CoQ10) during pregnancy alleviate preeclampsia symptoms and the underlying mechanism in the rats with preeclampsia. : Forty-five pregnant Wistar rats were equally divided into three groups randomly and received subcutaneous saline injection (control group, = 15) or 200 mg/kg L-NAME injection to induce preeclampsia symptoms (PE group, = 30). The PE rats were treated by distilled water (PE+DW group, = 15) and CoQ10 (PE+CoQ10 group, = 15) on day 15 to 21 of gestation randomly.

Mutual regulation between miR-21 and the TGFβ/Smad signaling pathway in human bronchial fibroblasts promotes airway remodeling.

Objective: Airway remodeling is an important pathological feature of asthma. Excessive deposition of extracellular matrix (e.g.

[Changes in serum inflammatory factors in wheezing infants with community-acquired pneumonia].

Objective: To study whether infantile wheezing pneumonia has similar immune mechanisms to asthma by determining the levels of serum inflammatory factors in wheezing infants with community-acquired pneumonia (CAP).

Methods: Forty-two infants with CAP but without wheezing, 47 infants with CAP and wheezing, and 30 healthy infants as a control were recruited in the study. The peripheral blood levels of C-reactive protein, procalcitonin, soluble triggering receptor expressed on myeloid cell-l, interferon-γ, interleukin-4, interleukin-10, and periostin were compared in the three groups.

[Roles of allergen testing in vitro and impulse oscillometry for lung function measurements in children with cough variant asthma].

Objective: To study the roles of allergen testing in vitro and impulse oscillometry for lung function measurements in preschool children with cough variant asthma (CVA).

Methods: ethodsForty-four preschool children with acute asthma, 41 with chronic asthma, 46 with CVA, and 35 healthy preschool children as control were recruited in the study. Inhaled allergen, food allergen, and mite-specific IgE were determined by Pharmacia UniCAP System.