Publications by authors named "Jian-Rong Na"

Article Synopsis
  • - Ongoing research shows that immunotherapy for advanced ovarian cancer has limited effectiveness when used alone, but combining it with other treatments can enhance its success.
  • - Biomarkers can help identify which patients are more likely to respond positively to immunotherapy, improving treatment precision; key biomarkers include factors like homologous repair deficiency and PD-L1 expression.
  • - The review discusses how studying biomarkers from genomics, transcriptomics, and proteomics perspectives can guide effective immunotherapy strategies for ovarian cancer in the future.
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Objective: This study aimed to provide a basis for epidemic prevention and control measures as well as the management of re-positive personnel by analyzing and summarizing the characteristics of re-positive patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant infections discharged from a hospital in the Ningxia Hui Autonomous Region in 2021.

Methods: This case-control study included a total of 45 patients with Delta variant infections diagnosed in the Fourth People's Hospital of the Ningxia Hui Autonomous Region between October 17 and November 28, 2021. Based on the nucleic acid test results post-discharge, the patients were dichotomized into re-positive and non-re-positive groups.

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Pulmonary arterial hypertension (PAH) is a malignant disease with high mortality and closely involves the bone morphogenetic protein (BMP) pathway. Mutations in BMPR2 caused proliferation of pulmonary artery smooth muscle cells (PASMCs) leading to PAH. Isorhamnetin, one of the main naturally occurring flavonoids extracted from Hippophae rhamnoides L, shows antiinflammatory and anti-proliferative properties.

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