Comparative Analysis of KGF-2 and bFGF in Prevention of Excessive Wound Healing and Scar Formation in a Corneal Alkali Burn Model.

Purpose: Basic fibroblast growth factor (bFGF) is an effective drug for corneal injury. However, the explicit role of bFGF in corneal scar formation still remains unclear. Keratinocyte growth factor-2 (KGF-2) is associated with the treatment of wound healing.

Toxicology study of long-term administration of rhKGF-2 eye drops on rabbit corneas.

Keratinocyte growth factor -2 promotes corneal repair. Its mechanism of action involves regulating regeneration and migration of corneal cells, as well as activating corneal limbal stem cells. However, KGF-2 being a carcinogenic growth factor and its potential adverse effect in over dosage long-term treatment had not yet been reported.

Initial Subsurface Incorporation of Oxygen into Ru(0001): A Density Functional Theory Study.

The adsorption and diffusion of oxygen on Ru(0001) surfaces as a function of coverage are systematically investigated by using density functional theory. A high incorporation barrier of low-coverage adsorbed oxygen into the subsurface is discovered. Calculations show that the adsorption of additional on-surface oxygen can lower the penetration barrier dramatically.

Association of Lumican gene polymorphism with high myopia: a meta-analysis.

Purpose: Numerous studies have evaluated the association between the single-nucleotide polymorphism (SNP) (rs3759223, C→T) in Lumican gene and high myopia risk in the Chinese population. However, the results have been inconsistent. We therefore here examined whether the rs3759223 polymorphism confers high myopia risk by conducting a meta-analysis.

Phacoemulsification versus manual small-incision cataract surgery for age-related cataract: meta-analysis of randomized controlled trials.

Background: To compare outcomes of phacoemulsification (PE) with manual small-incision cataract surgery (MSICS) for age-related cataract.

Design: Meta-analysis.

Participants: Patients from previously reported randomized controlled trials (RCTs) of PE and MSICS with clinical outcomes.

A meta-analysis of primary dacryocystorhinostomy with and without silicone intubation.

Objective: To examine possible differences in success rates of primary dacryocystorhinostomy (DCR) with and without silicone intubation, and to find out whether the use of silicone tubes is beneficial.

Design: A literature search was conducted in the PubMed, EMBASE, and Cochrane Controlled Trials Register to identify potentially relevant controlled trials.

Methods: Language was restricted to English.

[Medpor plus titanic mesh implant in the repair of orbital blowout fractures].

Objective: To study the efficacy of porous polyethylene (Medpor) plus titanic mesh sheets in the repair of orbital blowout fractures.

Methods: A total of 20 patients underwent open surgical reduction with the combined usage of Medpor and titanic mesh. And they were followed up for average period of 14.

[Estimation of preoperative corneal power in patients with myopic LASIK based on postoperative corneal data measured from Orbscan II].

Objective: Compare the change of pre- and post-operative posterior corneal curvature measurements in peripheral fitting zones using the Orbscan II topographer in patients undergoing myopic laser in situ keratomileusis (LASIK). To establish a new ratio of the anterior and posterior corneal curvature for the calculation of preoperative total corneal power using postoperative corneal data alone in patients after LASIK.

Methods: Retrospectively analyzed the changes of posterior corneal curvature in peripheral 7 to 10 mm fitting zones in 151 right eyes (151 individuals) 3 month after LASIK as measured by Orbscan II.

[Orbscan II-assisted intraocular lens power calculation after LASIK].

Objective: To evaluate the accuracy of keratometric value derived from one zone of Orbscan II mean power map after Laser in situ keratomileusis (LASIK) in combination with Holladay IOL Consultant software to calculate the intraocular lens (IOL) power.

Methods: A two-part study was conducted at a referral practice. Part 1 was a prospective study of 118 eyes undergoing LASIK.