Publications by authors named "Jian-Qing Cheng"

Objective: To investigate the effects of ulinastatin (Uti) and low-molecular-weight heparin (Lmwh) on coagulation function and deep vein thrombosis (DVT) in patients undergoing hip joint replacement.

Methods: From March to December 2010 150 ASAI-II patients with average age of 72.5 (65 - 85) years undergoing hip joint replacement were randomly divided into 3 groups (n = 50 each): normal saline (NS) control group (Group C), Uti group (Group U) and Lmwh group (Group L).

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Objective: To evaluate the preventive effects of ulinastatin (Uti) on postoperative complications in elderly patients undergoing hip joint replacement.

Methods: From Angust 2009 to June 2010, 160 elderly patients undergoing selective hip joint replacement with ASA I to II were assessed according to American Society of Anesthesiologists classification, including 81 males and 79 females ranging in age from 65 to 83 years (mean 73.9 years).

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Article Synopsis
  • The study aimed to assess the impact of ulinastatin on cognitive disorders following hip replacement surgery in elderly patients aged 65 and older.
  • It involved 40 patients divided into two groups: one receiving ulinastatin and the other receiving a placebo (normal saline), with cognitive tests conducted preoperatively and three days post-surgery.
  • Results showed that the ulinastatin group had a significantly lower incidence of post-operative cognitive disorders (2.5%) compared to the control group (25%), along with better cognitive scores and lower serum S100beta levels after surgery.
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