Publications by authors named "Jian-Qiao Xu"
Article Synopsis
- Xiao-Ai Jie-Du decoction (XAJDD) is traditionally used to treat diffuse large B-cell lymphoma (DLBCL) with varying prescriptions tailored to patients' conditions.* -
- The study aimed to identify the core ingredients of XAJDD and understand how they work against DLBCL using data mining and in silico modeling.* -
- The core formula includes six herbs, and key components like astibin and quercetin were found to significantly inhibit DLBCL cell proliferation and promote apoptosis, helping to reveal the treatment's molecular mechanisms.*
Background: In sepsis, vitamin D binding protein (VDBP) has been shown to be low-expressed. The current study examined the relationship between serum VDBP level and liver injury in sepsis patients, as well as in a mouse model for sepsis and in cultured liver epithelial cell line exposed to lipopolysaccharide (LPS).
Methods: The human study included 78 sepsis patients and 50 healthy volunteers.
Immunosuppression is currently a vital pathophysiological characteristic and core problem of sepsis. Apoptosis of T lymphocyte contribute to immunosuppression by decreasing immune effector cells. A report has recently revealed the potential regulatory role of exosomal miRNAs derived from plasma of septic patients on immune system, but the underlying mechanism is unclear.
View Article and Find Full Text PDF