Publications by authors named "Jian-Lin Hu"

The power industry is the main source of carbon dioxide (CO) emissions in Jiangsu Province and also an important source of sulfur dioxide (SO), nitrogen oxides (NO), and particulate matter (PM). In order to address climate change and contribute to the goal of "carbon peaking and carbon neutrality," Jiangsu Province has implemented a series of low-carbon development policies in the power industry. These policies not only reduce carbon emissions but also have important synergistic emission reduction benefits for atmospheric pollutants.

View Article and Find Full Text PDF
Article Synopsis
  • Ozone (O) has become a critical air pollutant in China, and understanding its sensitivity to volatile organic compounds (VOCs) and nitrogen oxides (NO) is essential for creating effective pollution control strategies.
  • This study evaluated three methods for determining O sensitivity during a pollution event in Nanjing: a photochemical indicator, sensitivity coefficients from a three-dimensional air quality model, and an observation-based model (OBM).
  • Results showed that while the photochemical indicator and sensitivity coefficients suggested similar patterns in O sensitivity, the OBM's accuracy was affected by data quality, leading to notable differences in the conditions identified, particularly during high pollution periods.
View Article and Find Full Text PDF

Based on the hourly concentration data of fine particulate matter (PM) and ozone (O) in Nanjing from 2015 to 2019, the synoptic situation that occurred in Nanjing, in which high PM and high O coexisted (hereinafter referred to as double high pollution (DHP)), was typed using T-mode principal component analysis. Additionally, the backward trajectory clustering analysis method, potential source contribution method (PSCF), and concentration weight trajectory analysis method (CWT) were used to study the transport paths and potential source region distribution of the DHP of Nanjing by different synoptic situations. The synoptic situations favorable to the DHP in Nanjing were the control of weak low-pressure type (Type1) and high-pressure center (Type2).

View Article and Find Full Text PDF

In recent years, regional compound air pollution events caused by fine particles (PM) and ozone (O) have occurred frequently in economically developed areas of China, in which atmospheric oxidizing capacity (AOC) has played an important role. In this study, the WRF-CMAQ model was used to study the impacts of anthropogenic emission reduction on AOC during the COVID-19 lockdown period. Three representative cities in eastern China (Shijiazhuang, Nanjing, and Guangzhou) were selected for an in-depth analysis to quantify the contribution of meteorology and emissions to the changes in AOC and oxidants and to discuss the impact of AOC changes on the formation of secondary pollutants.

View Article and Find Full Text PDF

This study applied a de-weather method based on a machine learning technique to quantify the contribution of meteorology and emission changes to air quality from 2015 to 2021 in four cities in the Yangtze River Delta Region. The results showed that the significant reductions in PM, NO, and SO emissions(57.2%-68.

View Article and Find Full Text PDF
Article Synopsis
  • * Research using atmospheric chemistry models and the random forest algorithm predicts PM and O concentration changes in Nanjing based on different human emission reduction scenarios.
  • * Simulations suggest a 10% reduction in emissions could lower PM levels substantially, potentially dropping below national limits, while reducing O precursor emissions could unintentionally raise O concentrations.
View Article and Find Full Text PDF

Based on the observation data of volatile organic compounds (VOCs) in the industrial area of Shenyang during the summer of 2019 and 2020, the composition characteristics and sources of VOCs were preliminarily studied. The ozone formation potential (OFP) and aerosol formation potential (AFP) of VOCs were also estimated using the max incremental reactivity (MIR) and aerosol formation coefficient (FAC) methods, respectively. The results showed that the average concentration of VOCs was 41.

View Article and Find Full Text PDF

In this study, 24-hour backward trajectories of the air mass in Nanjing were calculated by using the HYSPLIT model with the NCEP global reanalysis data from March 2019 to February 2020. The backward trajectories combined with the hourly concentration data of PM were then utilized in the trajectory clustering analysis and potential pollution source analysis. The results showed that the average concentration of PM in Nanjing was(36±20) μg·m during the study period, with 17 days exceeding the grade Ⅱ national ambient air quality standards (75 μg·m).

View Article and Find Full Text PDF

Meteorological conditions have important impacts on surface ozone (O) formation. To evaluate the influence of future climate change on O concentrations in different regions of China, this study employed the climate data from the community earth system model provided by the CMIP5 under the RCP4.5, RCP6.

View Article and Find Full Text PDF

The semi-/intermediate volatile organic compound (S/IVOCs) emissions inventory of Jiangsu province was established in 2019 using the activity data of various S/IVOCs emission sources, emission factors, and an estimation method. S/IVOCs emissions for each source and city in Jiangsu province were analyzed. The total amount of S/IVOCs emissions in Jiangsu province in 2019 was 637.

View Article and Find Full Text PDF

Three rare spirocyclohexadienone-type neolignans, magnoflorins A-C (1-3), and three known analogs (4-6), were isolated from the leaves of Magnolia liliiflora. Magnoflorin D (4) was obtained from natural resources for the first time. The chemical structures and absolute configurations of 1-4 were elucidated through detailed analysis of HR-ESI-MS, IR, H, C, and 2D NMR, and ECD experiments.

View Article and Find Full Text PDF

The corpus cavernosum is the most important structure for penile erection, and its dysfunction causes many physiological and psychological problems. However, its cellular heterogeneity and signalling networks at the molecular level are poorly understood because of limited access to samples. Here, we profile 64,993 human cavernosal single-cell transcriptomes from three males with normal erection and five organic erectile dysfunction patients.

View Article and Find Full Text PDF

The seasonal variation characteristics of water-soluble organic nitrogen (WSON) in PM were analyzed in the Nanjing Jiangbei new area. The relationship between WSON and water-soluble inorganic nitrogen (WSIN) was also discussed. The results showed that the variation range of WSON in PM was 0.

View Article and Find Full Text PDF

Cryopreservation of rare testicular-retrieved spermatozoa for intracytoplasmic sperm injection (ICSI) in patients with severe oligozoospermia and azoospermia remains a major challenge in clinical practice. This study evaluated the Cryopiece system as a potential technique to cryopreserve rare human spermatozoa for ICSI. Small numbers of ejaculated (24 patients) and testicular (13 patients) spermatozoa were cryopreserved using the Cryopiece system.

View Article and Find Full Text PDF

Accurate identification of species from timber is an essential step to help control illegal logging and forest loss. However, current approaches to timber identification based on morphological and anatomical characteristics have limited species resolution. DNA barcoding is a proven tool for plant species identification, but there is a need to build reliable reference data across broad taxonomic and spatial scales.

View Article and Find Full Text PDF

Background: Systematic reviews have focused on sperm recovery and post-thaw parameters after cryopreservation, but there is no information on the associated clinical outcomes. In recent years, an increasing number of studies have reported cryopreservation of a single sperm due to the importance of fertility preservation.

Objectives: To assess whether the cryopreservation of single human spermatozoa improves clinical outcomes in patients with azoospermia or severe oligospermia.

View Article and Find Full Text PDF

Background: Cryopreservation of extremely few spermatozoa is still a major challenge for male fertility preservation. This study aims to evaluate the cooling rate, recovery rate, and retrieval rate, along with other parameters of spermatozoa that cryopreserved using Cryopiece, a novel carrier, for individual sperm cryopreservation.

Methods: Semen samples from 60 fertile donors were collected, and each semen sample was screened for motile sperm and mixed with cryoprotective agent (CPA), and then frozen using Cryopiece, micro-straw, and mini-straws.

View Article and Find Full Text PDF

In this study, the 24-hour backward trajectories of air mass at ground level(10 m)in Nanjing were calculated by using the HYSPLIT model with the NCEP global reanalysis data from April 1st to October 31st, 2017. The backward trajectories were then combined with the hourly concentration data of O in Nanjing for trajectories clustering analysis and potential pollution sources analysis. The results show that in 2017, the maximum daily 8 h running average O level in Nanjing was around 12-261 μg·m with 58 days of O pollution in Nanjing, mainly in the spring and summer.

View Article and Find Full Text PDF

With the constraint that all six major pollutants in Nanjing must meet the air quality standards by 2030, on the basis of the 2015 emission inventory, the CMAQ air quality model was used to conduct PM sensitivity tests, and scenario analysis was used to predict the emission inventory and the air quality of four emission reduction scenarios were simulated. Finally, the total control index under the constraint of meeting the standards was obtained. The results show that primary particulate matter (PPM) reduction is the most effective at reducing the concentration of PM in the atmosphere, on the basis of emission reduction in surrounding areas, PPM emission reduction accounts for 88% of the total reduction of the annual average concentration of PM, followed by NH, NO, SO, and VOCs, which contribute to 10.

View Article and Find Full Text PDF

Structural alterations in fibroelastic components of the penile corpus cavernousum (CC) may impair its compliance, resulting in venous leakage and erectile dysfunction (ED). Our study evaluated the effectiveness of noninvasive two-dimensional shear-wave elastography (2-D SWE) in quantifying penile CC lesions in rabbits with hyperlipidemia-induced ED. A total of 12 New Zealand white rabbits were randomly divided into two groups.

View Article and Find Full Text PDF

Objective: To observe the effect of Huangjing Zanyu Capsule (HZC) on sperm mitochondrial membrane potential (MMP) in asthenozoospermia patients.

Methods: We assigned 70 asthenozoospermia patients to a treatment group (n = 39) and a control group (n = 31), the former treated with oral HZC at the dose of 4 capsules tid for 3 months while the latter left untreated. We obtained semen parameters from the patients and detected their sperm mitochondrial membrane potentials (MMP) by JC-1 staining and flow cytometry before and after medication, followed by comparison between the two groups.

View Article and Find Full Text PDF

Background: Emergence agitation (EA) is a common phenomenon in preschool children during emergence from general anesthesia. This study evaluated the safety and efficacy of dezocine for emergence agitation in preschool children anesthetized with sevoflurane-remifentanil.

Methods: A total of 100 preschool children, scheduled for elective laparoscopic repair of an inguinal hernia by high ligation of the hernia sac under sevoflurane-remifentanil anesthesia were randomized into two groups: Group C (n = 50) received Ringer's lactate 10 mL and Group D received Ringer's lactate 10 mL containing dezocine 0.

View Article and Find Full Text PDF

Although peroxisome proliferator-activated receptor-γ (PPARγ) and adenosine A2A receptor (A2AR) are reported to be anti-inflammatory factors in acute lung injury (ALI), their internal link and synergic or antagonistic effect after activation are poorly understood. Here, we found that PPARγ and A2AR could upregulate the mRNA and protein expressions of each other in lung tissues of LPS-induced mouse ALI model and murine macrophages. Further investigation demonstrated that PPARγ upregulated A2AR expression by directly binding to a DR10 response element (-218 to -197) within A2AR gene promoter region.

View Article and Find Full Text PDF

Purpose: We prospectively compared clinical response and penile color duplex ultrasound results of oral tadalafil 20 mg plus low dose intracavernous injection of vasoactive agents with those of intracavernous injection and oral tadalafil 20 mg alone. We also observed the best approach to facilitate penile color duplex ultrasound and that most preferred by patients.

Materials And Methods: All 56 patients with erectile dysfunction underwent penile color duplex ultrasound 3 times at an interval of at least 1 week using different pharmacological induction methods, including tadalafil mode (20 mg tadalafil), intracavernous injection mode (30 to 60 mg papaverine) and mixed mode (15 mg papaverine plus 20 mg tadalafil).

View Article and Find Full Text PDF

The antagonism or genetic deletion of adenosine A(2A) receptors has been shown to exacerbate tissue damage in acute lung injury. Caffeine, a widely consumed behavioral drug, acts as a non-selective antagonist of A(2A) receptor and also has additional pharmacological effects. Thus, the protective vs.

View Article and Find Full Text PDF