Publications by authors named "Jian-Lin Guo"
Background: Gastric cancer (GC) is a malignant tumour that originates in the gastric mucosal epithelium and is associated with high mortality rates worldwide. Long noncoding RNAs (lncRNAs) have been identified to play an important role in the development of various tumours, including GC. Yet, lncRNA biomarkers in a competing endogenous RNA network (ceRNA network) that are used to predict survival prognosis remain lacking.
View Article and Find Full Text PDFThe newt has the powerful capacity to regenerate lost limbs following amputation, and represents an excellent model organism to study regenerative processes. However, the molecular basis of the adaptive response in the regenerating limb of the Chinese fire-bellied newt Cynops orientalis immediately after amputation remains unclear. To better understand the adaptive response immediately after limb amputation at the protein level, we used isobaric tags for relative and absolute quantitation (iTRAQ) coupled with LC-MS/MS methods to analyze changes in the proteome of the regenerating newt limb that occurred 2 h and 8 h after amputation.
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- The study examined the effects of different doses of Ficus carica polysaccharide (FCP) on gene expressions related to immunity in grass carp when supplemented in their feed.
- Results showed that FCP significantly increased the expression of immune-related genes IL-1β and TNF-α, while reducing HSP70 expression.
- The fish fed with FCP exhibited improved immune responses and a higher survival rate (60%) against Flavobacterium columnare compared to the control group (30%).
Background: Dioscorea is an important plant genus in terms of food supply and pharmaceutical applications. However, its classification and identification are controversial. DNA barcoding is a recent aid to taxonomic identification and uses a short standardized DNA region to discriminate plant species.
View Article and Find Full Text PDFBackground: Cottonseed meal, an important source of feed raw materials, has limited use in the feed industry because of the presence of the highly toxic gossypol. The aim of the current work was to isolate the gossypol-degrading fungus from a soil microcosm and investigate the proteins involved in gossypol degradation.
Results: A fungal strain, AN-1, that uses gossypol as its sole carbon source was isolated and identified as Aspergillus niger.