Antitumor activity of miR-188-3p in gastric cancer is achieved by targeting CBL expression and inactivating the AKT/mTOR signaling.

Background: Altered miR-188-3p expression has been observed in various human cancers.

Aim: To investigate the miR-188-3p expression, its roles, and underlying molecular events in gastric cancer.

Methods: Fifty gastric cancer and paired normal tissues were collected to analyze miR-188-3p and CBL expression.

Human hepatocellular adenoma as a promising cell source for bioartificial liver systems.

The present study assessed human hepatocellular adenoma (HCA) as a potential source of biological material for bioartificial liver (BAL) systems. The histological characteristics of HCA tissues from 8 patients were examined using hematoxylin and eosin staining. The glycogen synthesis capacity of HCA cells was assessed using Periodic Acid-Schiff (PAS) staining and the expression of genes involved in liver function were examined using immunohistochemical staining (IHC) and reverse transcription-quantitative PCR analysis.