Publications by authors named "Jian-Jiang Jin"
Background: Prostate adenocarcinoma is a frequent cancer among men with high incidence and mortality rates. Biomarkers are useful for the treatment of cancers, so we need to explore the regulatory network of prostate adenocarcinoma.
Method: The database from University of California Santa Cruz was used to determine expression of messenger RNAs and microRNAs.
Article Synopsis
- Colon adenocarcinoma (COAD), a common cancer affecting both genders, shows a significant increase in the expression of collagen type I alpha 2 (COL1A2), which is linked to tumor development.
- Research involved bioinformatics assessments and immunohistochemistry to investigate COL1A2's expression and its potential as a prognostic indicator in COAD.
- Findings indicate that higher COL1A2 levels correlate with advanced cancer stages and poorer survival outcomes, indicating its role as a promising independent biomarker and target for COAD treatment.