Synopsis of recent research by authors named "Jian-Hua Shen"
- Jian-hua Shen's recent research has focused on the therapeutic effects of TGR5 agonists in intestinal health, specifically examining how selective TGR5 agonists like OM8 inhibit intestinal epithelial cell apoptosis and potentially ameliorate ulcerative colitis.
- His exploration of natural compounds such as coronarin A highlights their capability to modulate hepatic glucose metabolism, enhancing glycogen synthesis while inhibiting gluconeogenesis, thereby improving glucose homeostasis in diabetic mice.
- Shen's investigations encompass environmental health as well, with studies evaluating the effects of biogas slurry and straw application on the movement of heavy metals in agricultural soils, underscoring the intersection of agriculture and sustainability.
