Serum liver enzymes and risk of stroke: Systematic review with meta-analyses and Mendelian randomization studies.

Background And Purpose: Previous observational studies have identified correlations between liver enzyme levels and stroke risk. However, the strength and consistency of these associations vary. To comprehensively evaluate the relationship between liver enzymes and stroke risk, we conducted meta-analyses complemented by Mendelian randomization (MR) analyses.

Apolipoprotein E promotes white matter remodeling via the Dab1-dependent pathway after traumatic brain injury.

Introduction: Axonal injury results in long-term neurological deficits in traumatic brain injury (TBI) patients. Apolipoprotein E (ApoE) has been reported to activate intracellular adaptor protein Disabled-1 (Dab1) phosphorylation via its interaction with ApoE receptors. The Dab1 pathway acts as a regulator of axonal outgrowth and growth cone formation in the brain.

[Expression of Translocator Protein in Early Brain Injury After Subarachnoid Hemorrhage in Mice].

Objective: To evaluate the expression of translocator protein (TSPO) in brain tissue within 72 h after subarachnoid hemorrhage (SAH) in mice.

Methods: Forty-four C57BL/6J mice were randomly divided into two groups, 17 in the Sham group and 27 in the SAH group. SAH mice model was performed by endovascular perforation as previously described with slight modifications.

[Phosphorus Forms and Distribution Characteristics in the Sediment and Soil of the Water-Level-fluctuating Zone in the Main Stream of the Three Gorges Reservoir].

Hydrological regimes changed after the Three Gorges Reservoir (TGR) became fully operational, with the water level fluctuating between 145 m and 175 m. This has altered phosphorus (P) distribution within sediments and soils of the water-level-fluctuating zone (WLFZ). Eleven field investigations within the main stream were carried out in June 2016.

Pannus inflammation in sacroiliitis following immune pathological injury and radiological structural damage: a study of 193 patients with spondyloarthritis.

Background: The pathogenesis of sacroiliitis is unclear; therefore, we aimed to systematically study the immunopathology of sacroiliitis in patients with axial spondyloarthritis (axSpA), and explore the relationship between pannus formation, inflammation, and the structural damage caused by sacroiliitis.

Methods: Fine needle aspiration biopsy of the sacroiliac joint (SIJ) was performed in 193 patients with axSpA. Clinical, laboratory, and imaging data were collected at baseline and during the follow up.

Peli1 Contributions in Microglial Activation, Neuroinflammatory Responses and Neurological Deficits Following Experimental Subarachnoid Hemorrhage.

Early brain injury (EBI) following subarachnoid hemorrhage (SAH) is closely associated with neuroinflammation. Microglial activation is an early event that leads to neuroinflammation after SAH. Peli1 is an E3 ubiquitin ligase that mediates the induction of pro-inflammatory cytokines in microglia.

Apolipoprotein E ε4: A Possible Risk Factor of Intracranial Pressure and White Matter Perfusion in Good-Grade Aneurysmal Subarachnoid Hemorrhage Patients at Early Stage.

Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating and complicated disease with significant morbidity and mortality. Previous studies have shown that genetic susceptibility may play an important role in the outcome of a given individual with aSAH. This study evaluates the potential association in effects of the APOE allele on the early brain injury (EBI) in light of elevated intracranial pressure (ICP) and cerebral perfusion disorders in a consecutive series of non-comatose Chinese patients with aSAH.

[Analysis of Volatile Oils from Different Processed Products of Zingiber officinale Rhizome by GC-MS].

Objective: To analyze the volatile components in different processed products of Zingiber officinale rhizome, and to make clear the effect of different heating degree on them.

Methods: The volatile components were extracted from four kinds of processed products by applying steam distillation, and then were analyzed by GC-MS.

Results: There were totally 43 components of volatile oil identified from four kinds of processed products of Zingiber officinale rhizome.

Changes in the Prevalence of Rheumatic Diseases in Shantou, China, in the Past Three Decades: A COPCORD Study.

This study aimed to clarify changes in the prevalence of rheumatic diseases in Shantou, China, in the past 3 decades and validate whether stair-climbing is a risk factor for knee pain and knee osteoarthritis (KOA). The World Health Organization-International League Against Rheumatism Community Oriented Program for Control of Rheumatic Diseases (COPCORD) protocol was implemented. In all, 2337 adults living in buildings without elevators and 1719 adults living in buildings with elevators were surveyed.

[Comparison of postoperative deglutition disorder in patients with laryngeal carcinoma after different types of supracricoid partial laryngectomy].

Objective: To Evaluate the incidence rates and extents of deglutition disorder in patients with laryngeal carcinoma after different types of supracricoid partial laryngectomy.

Methods: Retrospective analysis of postoperative deglutition disorder in patients with laryngeal carcinoma after different types of supracricoid partial laryngectomy treated in our department from 2005 to 2009. The extents of postoperative deglutition disorder were evaluated using a homemade quantitative score table at 5-20 days postoperation.

Recreational noise exposure decreases olivocochlear efferent reflex strength in young adults.

Objective: To investigate effects of recreational noise exposure on olivocochlear efferent function.

Methods: efferent suppression of DPOAEs and acoustic reflexes were tested in 32 young personal listening device users with normal hearing and compared with that of healthy, non-noise-exposed young adults.

Results: The results showed that the efferent suppression of DPOAEs was mainly at low frequencies (0.

[Comparing extended vertical partial laryngectomy and cricohyoidoepiglottopexy in the treatment of laryngeal carcinoma].

Objective: To compare the results of extended vertical partial laryngectomy (similar to modified supracricoid partial laryngectomy with cricohyoidoepiglottopexy) and cricohyoidoepiglottopexy in the treatment of laryngeal carcinoma.

Methods: Retrospectively analyzed on the results and prognosis in patients underwent extended vertical partial laryngectomy and cricohyoidoepiglottopexy between 1998 and 2005. The operation was similar to extended vertical partial laryngectomy.

Long-term administration of salicylate enhances prestin expression in rat cochlea.

Salicylate, a common drug frequently used long term in the clinic, is well known for causing reversible hearing loss and tinnitus. Our previous study, however, demonstrated that chronic administration of salicylate progressively raised the amplitude of distortion product of otoacoustic emissions (DPOAEs), which are mainly caused by (outer hair cell) OHC electromotility. How salicylate affects OHC electromotility to cause this paradoxical increase remains unclear.

Risk of damage to hearing from personal listening devices in young adults.

Objective: To investigate the effects of personal listening device use on hearing in young listeners.

Methods: Conventional frequency audiometry (0.5-8 kHz) and extended high-frequency audiometry (10-20 kHz) were performed on 120 personal listening device users and 30 normal-hearing young adults.

[A clinical study of Safflower Yellow injection in treating coronary heart disease angina pectoris with Xin-blood stagnation syndrome].

Objective: To evaluate the clinical effect and safety of Safflower Yellow injection (SYI) in treating coronary heart disease angina pectoris (CHD-AP) with Xin-blood stagnation syndrome (XBSS).

Methods: Adopted was the multi-centered, randomized, positive parallel controlled method, 448 patients with CHD-AP-XBSS were enrolled and divided into two groups, 336 in the tested group treated with SYI and 112 in the control group treated with Salvia injection by intravenous dripping once a day for 14 days, so as to observe the conditions of angina, electrocardiogram, and therapeutic effect on traditional Chinese medicine (TCM) symptoms as well as the safety of the treatment.

Results: The significantly effective rate and total effective rate in the tested group were 60.

Continuous control of chaos based on the stability criterion.

A method of chaos control based on stability criterion is proposed in the present paper. This method can stabilize chaotic systems onto a desired periodic orbit by a small time-continuous perturbation nonlinear feedback. This method does not require linearization of the system around the stabilized orbit and only an approximate location of the desired periodic orbit is required which can be automatically detected in the control process.

Control and synchronization of chaos in high dimensional systems: Review of some recent results.

Controlling chaos and synchronization of chaos have evolved for a number of years as essentially two separate areas of research. Only recently it has been realized that both subjects share a common root in control theory. In addition, as limitations of low dimensional chaotic systems in modeling real world phenomena become increasingly apparent, investigations into the control and synchronization of high dimensional chaotic systems are beginning to attract more interest.