[Sorption and Transport of Antibiotics in Manured Upland Agricultural Soils].

Sorption and transport are important environmental behaviors of antibiotics in soils and can determine the fate of antibiotics in environments； however, limited relevant studies have been conducted on long-term manured soils. In this study, batch and repacked soil column experiments were conducted to examine the sorption and transport behavior of four veterinary antibiotics, including sulfamethazine （SMT）, florfenicol （FFC）, doxycycline （DOX）, and enrofloxacin （ENR）, in red soils, yellow soils, and calcareous soils with long-term amendment of chicken or pig manure collected in Zhejiang Province. The results showed that the sorption isothermal data of the four target antibiotics all conformed well to the linear and Freundlich models.

Biochar reduces antibiotic transport by altering soil hydrology and enhancing antibiotic sorption.

The performance of biochar (BC) in reducing the transport of antibiotics under field conditions has not been sufficiently explored. In repacked sloping boxes of a calcareous soil, the effects of different BC treatments on the discharge of three relatively weakly sorbing antibiotics (sulfadiazine, sulfamethazine, and florfenicol) via runoff and drainage were monitored for three natural rain events. Surface application of 1 % BC (1 %BC-SA) led to the most effective reduction in runoff discharge of the two sulfonamide antibiotics, which can be partly ascribed to the enhanced water infiltration.

[Adsorption Properties of Magnetic Phosphorous Camellia Oleifera Shells Biochar to Sulfamethoxazole in Water].

Magnetic phosphorous biochar （MPBC） was prepared from Camellia oleifera shells using phosphoric acid activation and iron co-deposition. The materials were characterized and analyzed through scanning electron microscopy （SEM）， X-ray diffractometry （XRD）， specific surface area and pore size analysis （BET）， Fourier infrared spectroscopy （FT-IR）， and X-ray photoelectron spectroscopy （XPS）. MPBC had a high surface area （1 139.

[Characteristics of Antibiotic Resistance Genes Distribution in Different Types of Agricultural Land Soils in Highly Cultivated Hilly Areas].

To characterize the distribution of antibiotic resistance genes(ARGs) in different types of agricultural soil in highly cultivated hilly areas, the abundance and diversity of ARGs in vegetable, orchard, and arable soils were analyzed in this study. The results showed that 70 ARGs and four mobile genetic elements(MGEs) were detected in all soil samples, with -lactam being the most abundant genes in the agricultural soils. In vegetable and orchard soils, the main ARG subtypes were and () genes, whereas the and genes were predominant in cropland soils.

A novel tool for tracing water sources of streamflow in a mixed land-use catchment.

Tracing water sources of streamflow in a mixed land-use catchment is critical for predicting pollutant emissions from various human activities to streams but remains a major challenge. A rain event based field monitoring study was conducted in the Jieliu catchment located in the hilly area of central Sichuan Province, southwest China. The ratio of the maximum fluorescence intensities (F) of the two humic-like dissolved organic matter (DOM) components at excitation/emission wavelengths of 255 (315)/415 nm (component 1; C1) and 260 (375)/480 nm (component 2; C2) was proposed as a tracer for quantifying streamflow water sources.

[Effect of Manure Application on the Adsorption of Antibiotics to Soil].

Sulfonamide antibiotics and florfenicol(FFC) are commonly used antibiotics in Zhejiang Province. They have weak adsorption on soil and are easy to migrate, with high environmental risks. In recent years, most of the studies on the potential risk of fecal-derived antibiotics to farmland soil were conducted by adding manure under laboratory conditions; therefore, it is impossible to assess the risk of antibiotic pollution under natural fertilization.

[Efficiency and Mechanism of O-SBBR Combined Process for Advanced Treatment of Biochemical Effluent from Printing and Dyeing Industrial Park].

With the aim of addressing the difficult problem of biodegradable organic nitrogen in biochemical effluent of a printing and dyeing industrial park, the combined ozonation-sequencing batch biofilm reactor (O-SBBR) process was used for advanced treatment. The influencing factors and degradation kinetics were analyzed; quenching experiments were carried out; and the types of free radicals, succinate dehydrogenase activity, and denitrification function genes were determined. The results showed that the suitable ozonation condition was pH 8.

Distinct aggregate stratification of antibiotic resistome in farmland soil with long-term manure application.

Agricultural soils, which are closely linked to human health via food supply, have been recognized as an important reservoir for antibiotic resistance genes (ARGs). However, there is still a lack of knowledge regarding the role of soil aggregates in shaping ARG profile. In this study, we collected soils from long-term experimental farmland plots receiving inorganic and/or organic fertilizers and examined the patterns of antibiotic resistome distribution among differently sized soil aggregates using high-throughput quantitative polymerase chain reaction (HT-qPCR).

Occurrence of antibiotic resistome in farmland soils near phosphorus chemical industrial area.

Heavy metal pollution of soil surrounding phosphorus chemical industry has been a long-concerned problem; however, the occurrence of antibiotic resistance genes (ARGs) in farmland soils in its vicinity remains unexplored. In this study, variations of heavy metals, ARGs, mobile genetic elements (MGEs), and microbiome in surface soils of farmland along the prevailing downwind direction of a phosphorus chemical industrial zone were investigated. Cadmium (Cd) contents in soils close to the industrial zone (≤ 500 m away) were statistically higher than those at greater distances (1000 to 4000 m).

Field aging alters biochar's effect on antibiotic resistome in manured soil.

Current understanding of biochar's effect on antibiotic resistance genes (ARGs) in soil is limited, and whether the effect could change after long-term field aging remains largely unknown. In this study, we employed high-throughput quantitative PCR to assess the effect of biochar amendment on soil resistome as affected by three years of field aging. Application of fresh biochar significantly elevated the number and abundance of ARGs in the manured soil, but did not show such effect under pakchoi cultivation.

Clinical features, radiological profiles, pathological features and surgical outcomes of pituicytomas: a report of 11 cases and a pooled analysis of individual patient data.

Background: Pituicytoma is an extremely rare low-grade glial tumor that is closely related to the neurohypophysis axis. Most studies of pituicytomas include only several cases. To better understand this disease, we reviewed a series of cases of pituicytomas.

Investigation of hierarchically porous zeolitic imidazolate frameworks for highly efficient dye removal.

Treatment of textile water containing organic molecules as contaminants still remains a challenge and has become a central issue for environment remediation. Here, a nucleotide incorporated zeolitic imidazolate frameworks (NZIF) featuring hierarchically porous structure served as a potential adsorbent for removal of organic dye molecules. Adsorption isotherms of organic dyes were accurately described by Langmuir adsorption model with correlation coefficients of 0.

The Association Between Admission Anemia and Poststroke Depression.

Poststroke depression (PSD) is the most frequent and important neuropsychiatric problem afflicting these patients. Anemia is common in many of these individuals presenting with acute stroke. This study determined whether there is a relationship between anemia on hospital admission and PSD.

Combined therapy of intensive statin plus intravenous rt-PA in acute ischemic stroke: the INSPIRE randomized clinical trial.

Objective: To investigate the safety and efficacy of intensive statin in the acute phase of ischemic stroke after intravenous thrombolysis therapy.

Methods: A total of 310 stroke patients treated with rt-PA were randomly scheduled into the intensive statin group (rosuvastatin 20 mg daily × 14 days) and the control group (rosuvastatin 5 mg daily × 14 days). The primary clinical endpoint was excellent functional outcome (mRS ≤ 1) at 3 months, and the primary safety endpoint was symptomatic intracranial hemorrhage (sICH) in 90 days.

Pituitary metastasis from renal cell carcinoma: case report and review of the literature.

Pituitary metastasis(PM) from renal cell carcinoma(RCC) is rare, and is easy to be misdiagnosed. Here, we present a case of pituitary metastasis from clear-cell renal cell carcinoma(ccRCC) which was difficult to distinguish from other sellar region tumors. In addition, we systematically review the literature to find the characteristics of different tumors of the sellar region.

[Characteristics of Antibiotic Resistance Genes in Various Livestock Feedlot Soils of the Hilly Purple Soil Region].

Given the potential risk posed by antibiotic resistance genes (ARGs) to the eco-environment in the hilly purple soil region, which has been intensively utilized by human, surface soil samples were collected from feedlots of pig, chicken, and cattle farms and were analyzed for the diversity and abundance of ARGs using high-throughput QPCR. In total, 79 ARGs and 5 mobile genetic elements (MGEs) were detected across all samples. Among these genes, multidrug resistance genes were the most abundant type of ARGs.

Regulating the CCNB1 gene can affect cell proliferation and apoptosis in pituitary adenomas and activate epithelial-to-mesenchymal transition.

The aim of the present study was to investigate the role and potential regulatory mechanisms of cyclin B1 (CCNB1) in the proliferation, apoptosis and epithelial-to-mesenchymal transition (EMT) in pituitary adenomas. A total of 24 specimens were included in the present study. The expression levels of CCNB1 protein in two normal pituitary and 22 pituitary adenoma tissues were determined by western blotting.

Magnetic aluminum-based metal organic framework as a novel magnetic adsorbent for the effective removal of minocycline from aqueous solutions.

In this paper, FeO@MIL-68 (Al), a magnetic aluminum-based metal organic framework, was synthesized by a simple method and used as a novel and effective adsorbent for the removal of minocycline (MC) from aqueous solutions. The material was thoroughly characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), thermogravimetric analysis (TGA) and N adsorption isotherms. The characterization results showed that the original structure of MIL-68(Al) was unchanged by the addition of FeO nanoparticles, and that the obtained material had a strong magnetic response which also promoted its adsorption.

Dynamics and sources of colloids in shallow groundwater in lowland wells and fracture flow in sloping farmland.

Field-scale studies of natural colloid mobilization and transport in finely fractured aquifer as well as the source identification of groundwater colloids are of great importance to the safety of shallow groundwater. In this study, the daily monitoring of fracture flow from a sloping farmland plot and the biweekly monitoring of three lowland shallow wells within the same catchment were carried out simultaneously in 2013. The effects of physicochemical perturbations on groundwater colloid dynamics were explored in detail using partial redundancy analysis, structural equation modeling, Pearson correlation and multi-linear regression analyses.

Contrastive removal of oxytetracycline and chlortetracycline from aqueous solution on Al-MOF/GO granules.

The presence of tetracycline antibiotics (TCS) in the water and wastewater has raised growing concern due to its potential environmental impacts; thus, their removal is of high importance. In this study, a novel aluminum-based MOF/graphite oxide (Al-MOF/GO) granule was prepared as an adsorbent for the removal of TCS including oxytetracycline (OTC) and chlortetracycline (CTC). The adsorbent was characterized via XRD, FTIR, BET, SEM, and XPS methods.

Removal of tetracycline from aqueous solution by MOF/graphite oxide pellets: Preparation, characteristic, adsorption performance and mechanism.

Tetracycline (TC) as a typical antibiotic has been used extensively and detected in soil, surface water, ground water and drinking water, which results in toxic effect and bacterial resistance. In this study, aluminum-based metal organic framework/graphite oxide (MIL-68(Al)/GO) pellets were prepared through the addition of sodium alginate (SA), a natural crosslinking agent, and applied as a novel adsorbent for aqueous TC removal. The adsorption materials were characterized by scanning electron microscope (SEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), N adsorption-desorption analysis and X-ray photoelectron spectroscopy (XPS).

Effect of long-term manure slurry application on the occurrence of antibiotic resistance genes in arable purple soil (entisol).

The application of animal manure is a highly recommended traditional agricultural practice for soils of relatively low fertility. However, for the farmland purple soils that are widely distributed in the upper Yangtze River region, little knowledge has been established in previous studies about the changes in the antibiotic resistome upon manure amendment. In the present study, the impact of long-term pig manure slurry application on the occurrence of antibiotic resistance genes (ARGs) and bacterial community was assessed in arable calcareous purple soil using high-throughput quantitative polymerase chain reaction and Illumina sequencing.

The extracellular domain of Staphylococcus aureus LtaS binds insulin and induces insulin resistance during infection.

Insulin resistance is a risk factor for obesity and diabetes and predisposes individuals to Staphylococcus aureus colonization; however, the contribution of S. aureus to insulin resistance remains unclear. Here, we show that S.

Characteristics of the ischemic stroke patients whose seizures occur at stroke presentation at a single institution in Eastern China.

Purpose: We compared clinical characteristics and outcomes of the early-onset seizure post-stroke patients who had seizures occurring at stroke presentation (SSP) with other patients without SSP at a single institution in Eastern China.

Methods: We reviewed 20,947 ischemic stroke patients in our hospital electronic medical records system from January 2007 to December 2016. Among them, there were 91 (0.

Adsorption behavior of methyl orange onto an aluminum-based metal organic framework, MIL-68(Al).

MIL-68(Al), a powdered aluminum-based metal organic framework (MOF), was synthesized and used to explore its adsorption behavior toward methyl orange (MO). The adsorption isotherm, thermodynamics, kinetics, and some key operating factors as well as changes in the material's structure were investigated. The adsorption isotherm conformed to the Langmuir isotherm model and the maximum equilibrium adsorption capacity was 341.