Publications by authors named "Jian-Guo Tao"
Limited whole genome sequencing (WGS) studies in Asian populations result in a lack of representative reference panels, thus hindering the discovery of ancestry-specific variants. Here, we present the South and East Asian reference Database (SEAD) panel ( https://imputationserver.westlake.
View Article and Find Full Text PDFN6-methyladenosine (m6A) plays a key role in many biological processes. However, the function and evolutionary relationship of m6A-related genes in insects remain largely unknown. Here we analysed the phylogeny of m6A-related genes among 207 insect species and found that m6A-related genes are evolutionarily conserved in insects.
View Article and Find Full Text PDFArticle Synopsis
- The Westlake BioBank for Chinese (WBBC) pilot project includes 4,535 whole-genome sequences and 5,841 high-density genotyping samples, identifying over 81 million genetic variants.
- A population-specific reference panel and an online server have been created to enhance genetic analysis in the Chinese population, particularly for rare variants.
- The study highlights genetic selection in specific genes, as well as historical allelic variations related to alcohol metabolism, while also demonstrating genetic differences between North Han and South Han populations along geographical boundaries.
[Epidemiological study on semen quality of 562 volunteers aged 22-30].
Zhonghua Liu Xing Bing Xue Za Zhi
January 2004
Objective: This study is to understand the difference of semen quality among the different areas and the related factors.
Methods: Five hundred and sixty-two people were under from seven provinces.
Results: Results showed that the quantity and density of semen, the rate of moving forward semen, livability, percent age of normal formed semen and the total number of semen were statistically different among the seven areas.