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Publications by authors named "Jian-Guang Lu"

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Synopsis of recent research by authors named "Jian-Guang Lu"

  • - Jian-Guang Lu's research primarily investigates molecular mechanisms underlying laryngeal squamous cell carcinoma (LSCC), focusing on factors such as epithelial-mesenchymal transition, apoptosis, and the roles of specific proteins like Cyr61, integrins, and osteopontin in cancer progression and metastasis.
  • - Studies demonstrate that increased expression of key biomarkers, including KAI1/CD82, MRP1/CD9, and integrin subunits, correlates with poor prognosis, invasive behavior, and lymphatic metastasis in patients with laryngeal cancers.
  • - Lu's work emphasizes the therapeutic potential of targeting specific molecular pathways, such as the inhibition of integrin αv and the down-regulation of microRNAs and cyclins, proposing strategies for more effective treatment and management of LSCC.

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